TCF3 Antikörper (AA 75-180)

Produktnummer ABIN701605

Produktdetails anti-TCF3 Antikörper

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Bindungsspezifität: AA 75-180

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human eIF2 alpha

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TCF3 Antikörper (ABIN701605)

He, Long, Zhong, Fu, Li, Lin: "Sustained endoplasmic reticulum stress inhibits hepatocyte proliferation via downregulation of c-Met expression." in: Molecular and cellular biochemistry, Vol. 389, Issue 1-2, pp. 151-8, (2014) (PubMed).

Details zu TCF3

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Andere Bezeichnung: e2 alpha (TCF3 Produkte)

Synonyme: E2A antikoerper, E47 antikoerper, ITF1 antikoerper, TCF-3 antikoerper, VDIR antikoerper, bHLHb21 antikoerper, tcf3a antikoerper, zgc:113045 antikoerper, A1 antikoerper, AA408400 antikoerper, ALF2 antikoerper, AW209082 antikoerper, E12 antikoerper, E12/E47 antikoerper, ME2 antikoerper, Pan1 antikoerper, Pan2 antikoerper, Tcfe2a antikoerper, bhlhb21 antikoerper, e2a antikoerper, itf1 antikoerper, tcfe2a antikoerper, vdir antikoerper, xtcf-3 antikoerper, xtcf3 antikoerper, G12 antikoerper, TCF7L1 antikoerper, XE3 antikoerper, transcription factor 3 antikoerper, transcription factor 3b antikoerper, transcription factor 3 L homeolog antikoerper, transcription factor E2a antikoerper, TCF3 antikoerper, tcf3b antikoerper, Tcf3 antikoerper, tcf3.L antikoerper, tcfe2a antikoerper

Hintergrund:

Synonyms: EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, EIF2S1

Background: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 4S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 6S ribosomal subunit to form the 8S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Gen-ID: 1965

UniProt: P05198

Pathways: WNT Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response