TCF3 Antikörper

Produktnummer ABIN1724729

Produktdetails anti-TCF3 Antikörper

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human TCF3 expressed in E. coli.

Klon: 6B8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-TCF3 Antikörper (ABIN1724729)

Snider, Thirlwell, Miller, Moon, Groudine, Tapscott: "Inhibition of Tcf3 binding by I-mfa domain proteins." in: Molecular and cellular biology, Vol. 21, Issue 5, pp. 1866-73, (2001) (PubMed).

Firulli, Hadzic, McDaid, Firulli: "The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function." in: The Journal of biological chemistry, Vol. 275, Issue 43, pp. 33567-73, (2000) (PubMed).

Details zu TCF3

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Andere Bezeichnung: TCF3 (TCF3 Produkte)

Synonyme: E2A antikoerper, E47 antikoerper, ITF1 antikoerper, TCF-3 antikoerper, VDIR antikoerper, bHLHb21 antikoerper, tcf3a antikoerper, zgc:113045 antikoerper, A1 antikoerper, AA408400 antikoerper, ALF2 antikoerper, AW209082 antikoerper, E12 antikoerper, E12/E47 antikoerper, ME2 antikoerper, Pan1 antikoerper, Pan2 antikoerper, Tcfe2a antikoerper, bhlhb21 antikoerper, e2a antikoerper, itf1 antikoerper, tcfe2a antikoerper, vdir antikoerper, xtcf-3 antikoerper, xtcf3 antikoerper, G12 antikoerper, TCF7L1 antikoerper, XE3 antikoerper, transcription factor 3 antikoerper, transcription factor 3b antikoerper, transcription factor 3 L homeolog antikoerper, transcription factor E2a antikoerper, TCF3 antikoerper, tcf3b antikoerper, Tcf3 antikoerper, tcf3.L antikoerper, tcfe2a antikoerper

Hintergrund:

Description: Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

Aliases: E2A, ITF1, VDIR, bHLHb21, MGC129647, MGC129648, TCF3

Molekulargewicht: 67.6 kDa

Gen-ID: 6929

HGNC: 6929

Pathways: WNT Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response