TCF3 Antikörper (pThr355)

Produktnummer ABIN7138838

Produktdetails anti-TCF3 Antikörper

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Bindungsspezifität: pThr355

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 355 (P-S-T(p)-P-V) derived from Human E2A .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TCF3

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Andere Bezeichnung: TCF3 (TCF3 Produkte)

Synonyme: E2A antikoerper, E47 antikoerper, ITF1 antikoerper, TCF-3 antikoerper, VDIR antikoerper, bHLHb21 antikoerper, tcf3a antikoerper, zgc:113045 antikoerper, A1 antikoerper, AA408400 antikoerper, ALF2 antikoerper, AW209082 antikoerper, E12 antikoerper, E12/E47 antikoerper, ME2 antikoerper, Pan1 antikoerper, Pan2 antikoerper, Tcfe2a antikoerper, bhlhb21 antikoerper, e2a antikoerper, itf1 antikoerper, tcfe2a antikoerper, vdir antikoerper, xtcf-3 antikoerper, xtcf3 antikoerper, G12 antikoerper, TCF7L1 antikoerper, XE3 antikoerper, transcription factor 3 antikoerper, transcription factor 3b antikoerper, transcription factor 3 L homeolog antikoerper, transcription factor E2a antikoerper, TCF3 antikoerper, tcf3b antikoerper, Tcf3 antikoerper, tcf3.L antikoerper, tcfe2a antikoerper

Hintergrund:

Background:

E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.

Kamps M.P., Cell 60:547-555(1990).
Nourse J., Cell 60:535-545(1990).
Grimwood J., Nature 428:529-535(2004).

Aliases: AGM8 antibody, bHLHb21 antibody, Class B basic helix-loop-helix protein 21 antibody, E12 antibody, E2A antibody, E2A immunoglobulin enhancer binding factors E12/E47 antibody, E47 antibody, Helix loop helix protein HE47 antibody, Immunoglobulin enhancer-binding factor E12/E47 antibody, Immunoglobulin transcription factor 1 antibody, ITF1 antibody, Kappa-E2-binding factor antibody, MGC129647 antibody, MGC129648 antibody, Negative vitamin D response element binding protein antibody, NOL1-TCF3 fusion antibody, TCF-3 antibody, Tcf3 antibody, TFE2_HUMAN antibody, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) antibody, Transcription factor 3 antibody, transcription factor 3 variant 3 antibody, Transcription factor E2-alpha antibody, Transcription factor ITF-1 antibody, VDIR antibody, VDR interacting repressor antibody, vitamin D receptor-interacting repressor antibody

UniProt: P15923

Pathways: WNT Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response