PPP3CC Antikörper (AA 482-512)

Produktnummer ABIN3032391

Produktdetails anti-PPP3CC Antikörper

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Bindungsspezifität: AA 482-512

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP3CC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Purified

Immunogen: A portion of amino acids 482-512 from the human protein was used as the immunogen for this PPP3CC antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the PPP3CC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PPP3CC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Andere Bezeichnung: PPP3CC (PPP3CC Produkte)

Synonyme: CALNA3 antikoerper, CNA3 antikoerper, PP2Bgamma antikoerper, Calnc antikoerper, ppp3cc antikoerper, sb:cb767 antikoerper, si:dkey-21k4.5 antikoerper, calna3 antikoerper, cna3 antikoerper, pp2bgamma antikoerper, im:7163784 antikoerper, zgc:158685 antikoerper, protein phosphatase 3 catalytic subunit gamma antikoerper, protein phosphatase 3, catalytic subunit, gamma isoform antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme, a antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme L homeolog antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme, b antikoerper, PPP3CC antikoerper, Ppp3cc antikoerper, ppp3cca antikoerper, ppp3cc antikoerper, ppp3cc.L antikoerper, ppp3ccb antikoerper

Hintergrund: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma, have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).

UniProt: P48454

Pathways: RTK Signalweg, WNT Signalweg, VEGF Signaling, BCR Signaling