PPP3CC Antikörper (N-Term)

Produktnummer ABIN360812

Der Kaninchen Polyklonal anti-PPP3CC Antikörper wird verwendet zum Nachweis von PPP3CC in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für PPP3CC Antikörper (N-Term) (ABIN360812)

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP3CC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PPP3CC Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to PPP3CC.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PPP3CC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Andere Bezeichnung: PPP3CC / CALNA3

Hintergrund: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).Synonyms: CAM-PRP catalytic subunit, CNA3, Calcineurin testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, protein phosphatase 2B catalytic subunit gamma

Gen-ID: 5533

NCBI Accession: NP_005596

UniProt: P48454

Pathways: RTK Signalweg, WNT Signalweg, VEGF Signaling, BCR Signaling