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p21 Antikörper (AA 143-147)
CDKN1A
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-p21 Antikörper
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Target
Alle p21 (CDKN1A) Antikörper anzeigen
p21 (CDKN1A)
(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
Bindungsspezifität
Alle Epitope für p21 Antikörper
AA 143-147
Reaktivität
Alle Reaktivitäten für p21 Antikörper
Human
Wirt
Alle Wirte für p21 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für p21 Antikörper
Polyklonal
Konjugat
Alle Konjugate für p21 Antikörper
Dieser p21 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für p21 Antikörper
Western Blotting (WB)
Spezifität
This antibody detects endogenous levels of total p21Cip1 protein.
Aufreinigung
Immunoaffinity Chromatography.
Immunogen
Peptide Sequence around amino acids 143~147 (R-Q-T-S-M) derived from Human p21Cip1.
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Alternativen
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anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 21-100) antibody
CDKN1A
Reaktivität: Human, Maus, Ratte, Schaf
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Western Blot (1/500-1/1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody (in aliquots) at-20 °C.
Details zu p21
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Target
p21 (CDKN1A)
(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
Andere Bezeichnung
CDKN1A / p21WAF1 (CDKN1A Produkte )
Synonyme
CCND1 antikoerper, CDKN1A antikoerper, CAP20 antikoerper, CDKN1 antikoerper, CIP1 antikoerper, MDA-6 antikoerper, P21 antikoerper, SDI1 antikoerper, WAF1 antikoerper, p21CIP1 antikoerper, CDKI antikoerper, Cdkn1 antikoerper, Waf1 antikoerper, mda6 antikoerper, p21Cip1 antikoerper, p21WAF antikoerper, Cip1 antikoerper, UV96 antikoerper, p21 antikoerper, cip1 antikoerper, p16Xic2 antikoerper, sdi1 antikoerper, waf1 antikoerper, cap20 antikoerper, cdkn1 antikoerper, mda-6 antikoerper, p21cip1 antikoerper, si:ch1073-48m5.2 antikoerper, KRAS2 antikoerper, p21ras antikoerper, cyclin D1 antikoerper, cyclin dependent kinase inhibitor 1A antikoerper, cyclin-dependent kinase inhibitor 1A (P21) antikoerper, cyclin-dependent kinase inhibitor 1A antikoerper, cyclin-dependent kinase inhibitor 1A L homeolog antikoerper, cyclin-dependent kinase inhibitor 1 antikoerper, KRAS proto-oncogene, GTPase antikoerper, CCND1 antikoerper, CDKN1A antikoerper, Cdkn1a antikoerper, cdkn1a.L antikoerper, cki1 antikoerper, cdkn1a antikoerper, KRAS antikoerper
Hintergrund
Cell cycle progression is regulated by cyclins and their cognate Cdks. p21 (WAF1/CIP1) inhibits the activity of each member of the cyclin/Cdk family, and overexpression of this protein inhibits the proliferation of mammalian cells. The expression of p21 is inducible by a wide range of stress stimuli. p21 is tightly regulated at the transcriptional level by p53, and probably serves as the effector of p53 cell cycle control.Synonyms: CAP20, CDK-interacting protein 1, CDKN1, CIP1, Cyclin-dependent kinase inhibitor 1, MDA-6, MDA6, Melanoma differentiation-associated protein 6, PIC1, SDI1, WAF1
Gen-ID
1026
NCBI Accession
NP_000380
UniProt
P38936
Pathways
p53 Signalweg , PI3K-Akt Signalweg , Zellzyklus , AMPK Signaling , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Mitotic G1-G1/S Phases , DNA Replication , Hepatitis C , Synthesis of DNA , Autophagie
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