p21 Antikörper (AA 65-164)
Kurzübersicht für p21 Antikörper (AA 65-164) (ABIN560309)
Target
Alle p21 (CDKN1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 65-164
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Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant CDKN1A.
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Sequenz
- WERVRGLGLP KLYLPTGPRR GRDELGGGRR PGTSPALLQG TAEEDHVDLS LSCTLVPRSG EQAEGSPGGP GDSQGRKRRQ TSMTDFYHSK RRLIFSKRKP
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Kreuzreaktivität
- Human
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Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- CDKN1A (AAH00312.1, 65 a.a. ~ 164 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1x PBS, pH 7.4
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).
: "Phospho-?Np63? is a key regulator of the cisplatin-induced microRNAome in cancer cells." in: Cell death and differentiation, Vol. 18, Issue 7, pp. 1220-30, (2011) (PubMed).
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- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
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Andere Bezeichnung
- CDKN1A
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Hintergrund
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Full Gene Name: cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Synonyms: CAP20,CDKN1,CIP1,MDA-6,P21,SDI1,WAF1,p21CIP1 -
Gen-ID
- 1026
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NCBI Accession
- NM_000389
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagie
Target
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