BRAF Antikörper (AA 38-230)

Produktnummer ABIN3029546

Produktdetails anti-BRAF Antikörper

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Bindungsspezifität: AA 38-230

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 38-230) was used as the immunogen for this BRAF antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the BRAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized BRAF antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu BRAF

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Andere Bezeichnung: BRAF (BRAF Produkte)

Synonyme: B-RAF1 antikoerper, BRAF1 antikoerper, NS7 antikoerper, RAFB1 antikoerper, C-RMIL antikoerper, RMIL antikoerper, B-Raf antikoerper, braf1 antikoerper, rafb1 antikoerper, b-raf1 antikoerper, sierrabraf antikoerper, BRAF antikoerper, 9930012E13Rik antikoerper, AA120551 antikoerper, AA387315 antikoerper, AA473386 antikoerper, B-raf antikoerper, Braf-2 antikoerper, Braf2 antikoerper, C230098H17 antikoerper, C87398 antikoerper, D6Ertd631e antikoerper, braf antikoerper, fc48g01 antikoerper, wu:fc48g01 antikoerper, B-Raf proto-oncogene, serine/threonine kinase antikoerper, B-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Braf transforming gene antikoerper, si:dkey-222f8.3 antikoerper, BRAF antikoerper, Braf antikoerper, braf.S antikoerper, braf antikoerper, si:dkey-222f8.3 antikoerper

Hintergrund: BRAF (v-raf murine sarcoma viral oncogene homolog B1) is a human gene that makes a protein called B Raf. It is a member of the Raf kinase family of growth signal transduction protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. It is mapped to 7q34. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. The BRAF protein is also involved in sending signals inside cells, which are involved in directing cell growth.

Gen-ID: 673

Pathways: MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie