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JNK Antikörper (AA 245-345)

MAPK8 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3020887
  • Target Alle JNK (MAPK8) Antikörper anzeigen
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    Bindungsspezifität
    • 61
    • 28
    • 17
    • 16
    • 16
    • 10
    • 9
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 245-345
    Reaktivität
    • 213
    • 118
    • 101
    • 43
    • 34
    • 20
    • 18
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 195
    • 23
    • 3
    Kaninchen
    Klonalität
    • 179
    • 42
    Polyklonal
    Konjugat
    • 104
    • 18
    • 16
    • 14
    • 12
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Dieser JNK Antikörper ist unkonjugiert
    Applikation
    • 166
    • 93
    • 57
    • 42
    • 40
    • 39
    • 36
    • 31
    • 21
    • 18
    • 14
    • 12
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    CPEFMKKLQP TVRTYVENRP KYAGYSFEKL FPDVLFPADS EHNKLKASQA RDLLSKMLVI DASKRISVDE ALQHPYINVW YDPSEAEAPP PKIPDKQLDE R
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 245-345 of human JNK1 (NP_620635.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • He, Zhao, Anees, Li, Ashraf, Chen, Song, Chen, Cao, Ye: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).

    Li, Yu, Wang, Xu, Chi, Qin, Liu: "The ω-carboxyl group of 7-ketocholesteryl-9-carboxynonanoate mediates the binding of oxLDL to CD36 receptor and enhances caveolin-1 expression in macrophages." in: The international journal of biochemistry & cell biology, Vol. 90, pp. 121-135, (2017) (PubMed).

    Ma, Li, Yin, Liu, Gao, Lin, Huang, Huang, Li: "Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells." in: Free radical biology & medicine, Vol. 89, pp. 1003-13, (2016) (PubMed).

    Zhong, Wang, Liu, Li, Huang, Zhou, Lin, Lin, Yang: "Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress." in: Scientific reports, Vol. 5, pp. 16910, (2016) (PubMed).

  • Target
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    Andere Bezeichnung
    MAPK8 (MAPK8 Produkte)
    Synonyme
    JNK antikoerper, JNK-46 antikoerper, JNK1 antikoerper, JNK1A2 antikoerper, JNK21B1/2 antikoerper, PRKM8 antikoerper, SAPK1 antikoerper, SAPK1c antikoerper, AI849689 antikoerper, Prkm8 antikoerper, BSK antikoerper, BSK/DJNK antikoerper, Bsk antikoerper, CG5680 antikoerper, D-JNK antikoerper, D-junk antikoerper, DBSK/JNK antikoerper, DJNK antikoerper, DJNK/bsk antikoerper, Dmel\\CG5680 antikoerper, JNK/SAPK antikoerper, Jnk antikoerper, Junk antikoerper, SAPKa antikoerper, c-Jun antikoerper, dJNK antikoerper, jnk antikoerper, T10F20.15 antikoerper, jnk1 antikoerper, sapk1 antikoerper, mapk8 antikoerper, zgc:112379 antikoerper, JNKb antikoerper, mapk8b antikoerper, mitogen-activated protein kinase 8 antikoerper, Stress-activated protein kinase jnk-1 antikoerper, basket antikoerper, Protein kinase superfamily protein antikoerper, mitogen-activated protein kinase 8 L homeolog antikoerper, mitogen-activated protein kinase 8b antikoerper, mitogen-activated protein kinase 8B-like antikoerper, MAPK8 antikoerper, jnk-1 antikoerper, Mapk8 antikoerper, bsk antikoerper, ATMPK8 antikoerper, mapk8.L antikoerper, mapk8b antikoerper, LOC109094263 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.,MAPK8,JNK,JNK-46,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1,SAPK1c,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,MAPK8
    Molekulargewicht
    35 kDa/44 kDa/48 kDa
    Gen-ID
    5599
    UniProt
    P45983
    Pathways
    MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteine
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