Insulin Antikörper

Produktnummer ABIN295207

Produktdetails anti-Insulin Antikörper

Target: Insulin (INS)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Insulin Antikörper ist unkonjugiert

Applikation: ELISA

Spezifität: The site of connection of C-peptide and C-end of B-chain of proinsulin molecule. MAbs 1D6 and 1D3 react with different epitopes on human proinsulin molecule, both of each are generated by the interactions between insulin and C-peptide parts of prohormone. Kd MAb 3A1 is 1.1 x 10-8 M. Kd MAb 1G4 is 2.6 x 10-7 M. Kd MAb 1D6 and 1D3 is >3 x 10-8 M. Kd MAb 7D6 is >5 x 10-8 M. MAbs 3A1, 1G4, 1D6, 1D3 and 7D6 do not cross-react with human, bovine and porcine insulin, bovine and porcine proinsulin, and human C-peptide.

Aufreinigung: Protein A purified

Immunogen: Purified human proinsulin.

Type of Immunogen: Purified protein

Klon: 1D3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freezing

Lagerung: 4 °C

Informationen zur Lagerung: 4°C, avoid freezing.

Details zu Insulin

Target: Insulin (INS)

Andere Bezeichnung: Insulin (INS Produkte)

Synonyme: IDDM2 antikoerper, ILPR antikoerper, IRDN antikoerper, MODY10 antikoerper, ins1 antikoerper, xins antikoerper, ins1-a antikoerper, Insulin antikoerper, AA986540 antikoerper, Ins-2 antikoerper, InsII antikoerper, Mody antikoerper, Mody4 antikoerper, proinsulin antikoerper, zgc:109842 antikoerper, igf2-A antikoerper, ins antikoerper, ins-a antikoerper, ins-b antikoerper, insulin antikoerper, insulin precursor antikoerper, insulin II antikoerper, preproinsulin antikoerper, insulin L homeolog antikoerper, insulin S homeolog antikoerper, INS antikoerper, INS-IGF2 antikoerper, ins antikoerper, Ins antikoerper, PIN antikoerper, Ins2 antikoerper, ins.L antikoerper, ins.S antikoerper

Hintergrund: Name/Gene ID: INS
Family: Hormone

Synonyms: INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin

Gen-ID: 3630

UniProt: P01308

Pathways: NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation