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TNFRSF1B Antikörper (Biotin)
TNFRSF1B
Reaktivität: Maus
ELISA, IHC, FACS
Wirt: Hamster
Monoclonal
TR75-89
Biotin
Produktnummer ABIN2660924
Produktdetails anti-TNFRSF1B Antikörper (Biotin)
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Target
Alle TNFRSF1B Antikörper anzeigen
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Reaktivität
Alle Reaktivitäten für TNFRSF1B Antikörper
Maus
Wirt
Alle Wirte für TNFRSF1B Antikörper
Hamster
Klonalität
Alle Klonalitäten für TNFRSF1B Antikörper
Monoklonal
Konjugat
Alle Konjugate für TNFRSF1B Antikörper
Dieser TNFRSF1B Antikörper ist konjugiert mit Biotin
Applikation
Alle Applikationen für TNFRSF1B Antikörper
ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
Aufreinigung
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Klon
TR75-89
Isotyp
IgG
Top Product
Discover our top product TNFRSF1B Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu TNFRSF1B
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Target
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Andere Bezeichnung
CD120b (TNFRSF1B Produkte )
Synonyme
CD120b antikoerper, TBPII antikoerper, TNF-R-II antikoerper, TNF-R75 antikoerper, TNFBR antikoerper, TNFR1B antikoerper, TNFR2 antikoerper, TNFR80 antikoerper, p75 antikoerper, p75TNFR antikoerper, TNF-RII/TNFRSF1B antikoerper, TNFR-II antikoerper, TNFRSF1B antikoerper, TNF-R2 antikoerper, TNF-alphaR2 antikoerper, TNFRII antikoerper, TNFalpha-R2 antikoerper, Tnfr-1 antikoerper, Tnfr2 antikoerper, rank antikoerper, zgc:163064 antikoerper, TNF receptor superfamily member 1B antikoerper, tumor necrosis factor receptor superfamily, member 1b antikoerper, tumor necrosis factor receptor superfamily, member 1B antikoerper, TNFRSF1B antikoerper, Tnfrsf1b antikoerper, tnfrsf1b antikoerper
Hintergrund
CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels, the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
Pathways
NF-kappaB Signalweg , Apoptose , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Ubiquitin Proteasome Pathway
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