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TNFRSF1B Antikörper
TNFRSF1B
Reaktivität: Human, Maus, Ratte
IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN7257154
Produktdetails anti-TNFRSF1B Antikörper
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Target
Alle TNFRSF1B Antikörper anzeigen
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Reaktivität
Alle Reaktivitäten für TNFRSF1B Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für TNFRSF1B Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TNFRSF1B Antikörper
Polyklonal
Konjugat
Alle Konjugate für TNFRSF1B Antikörper
Dieser TNFRSF1B Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNFRSF1B Antikörper
Immunohistochemistry (IHC)
Produktmerkmale
Polyclonal Antibody
Aufreinigung
Affinity purification
Immunogen
Recombinant fusion protein of human TNFRSF1B (NP_001057.1).
Isotyp
IgG
Top Product
Discover our top product TNFRSF1B Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
IHC 1:50-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Details zu TNFRSF1B
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Target
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Andere Bezeichnung
TNFRSF1B (TNFRSF1B Produkte )
Synonyme
CD120b antikoerper, TBPII antikoerper, TNF-R-II antikoerper, TNF-R75 antikoerper, TNFBR antikoerper, TNFR1B antikoerper, TNFR2 antikoerper, TNFR80 antikoerper, p75 antikoerper, p75TNFR antikoerper, TNF-RII/TNFRSF1B antikoerper, TNFR-II antikoerper, TNFRSF1B antikoerper, TNF-R2 antikoerper, TNF-alphaR2 antikoerper, TNFRII antikoerper, TNFalpha-R2 antikoerper, Tnfr-1 antikoerper, Tnfr2 antikoerper, rank antikoerper, zgc:163064 antikoerper, TNF receptor superfamily member 1B antikoerper, tumor necrosis factor receptor superfamily, member 1b antikoerper, tumor necrosis factor receptor superfamily, member 1B antikoerper, TNFRSF1B antikoerper, Tnfrsf1b antikoerper, tnfrsf1b antikoerper
Hintergrund
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Gen-ID
7133
UniProt
P20333
Pathways
NF-kappaB Signalweg , Apoptose , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Ubiquitin Proteasome Pathway
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