TNFRSF1B Antikörper (AA 23-257)

Produktnummer ABIN7193268

Produktdetails anti-TNFRSF1B Antikörper

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Bindungsspezifität: AA 23-257

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CD120B (AA: extra 23-257) expressed in E. coli.

Klon: 7G8B6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu TNFRSF1B

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Andere Bezeichnung: CD120B (TNFRSF1B Produkte)

Synonyme: CD120b antikoerper, TBPII antikoerper, TNF-R-II antikoerper, TNF-R75 antikoerper, TNFBR antikoerper, TNFR1B antikoerper, TNFR2 antikoerper, TNFR80 antikoerper, p75 antikoerper, p75TNFR antikoerper, TNF-RII/TNFRSF1B antikoerper, TNFR-II antikoerper, TNFRSF1B antikoerper, TNF-R2 antikoerper, TNF-alphaR2 antikoerper, TNFRII antikoerper, TNFalpha-R2 antikoerper, Tnfr-1 antikoerper, Tnfr2 antikoerper, rank antikoerper, zgc:163064 antikoerper, TNF receptor superfamily member 1B antikoerper, tumor necrosis factor receptor superfamily, member 1b antikoerper, tumor necrosis factor receptor superfamily, member 1B antikoerper, TNFRSF1B antikoerper, Tnfrsf1b antikoerper, tnfrsf1b antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Aliases: TNFRSF1B, p75, TBPII, TNFBR, TNFR2, TNFR1B, TNFR80, TNF-R75, p75TNFR, TNF-R-II

Molekulargewicht: 48.3 kDa

Gen-ID: 7133

Pathways: NF-kappaB Signalweg, Apoptose, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway