MAP2K7 Antikörper (pThr275)

Produktnummer ABIN2568342

Produktdetails anti-MAP2K7 Antikörper

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Bindungsspezifität: pThr275

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous levels of MAP2K7 only when phosphorylated at threonine 275.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: MAP2K7 (phospho Thr275) antibody was raised against a peptide sequence around phosphorylation site of threonine 275 (A-K-T (p)-R-S) derived from Human MAP2K7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu MAP2K7

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Andere Bezeichnung: MAP2K7 (MAP2K7 Produkte)

Synonyme: MAP2K7 antikoerper, 2 antikoerper, JNKK antikoerper, Jnkk2 antikoerper, Mapkk7 antikoerper, Mek7 antikoerper, Mkk7 antikoerper, MAPKK7 antikoerper, MKK7 antikoerper, PRKMK7 antikoerper, SAPKK-4 antikoerper, SAPKK4 antikoerper, 5930412N11Rik antikoerper, JNKK 2 antikoerper, MAPKK 7 antikoerper, MEK 7 antikoerper, Prkmk7 antikoerper, sek2 antikoerper, si:ch211-254d18.2 antikoerper, map2k7-A antikoerper, mitogen-activated protein kinase kinase 7 antikoerper, mitogen activated protein kinase kinase 7 antikoerper, mitogen-activated protein kinase kinase 7 L homeolog antikoerper, MAP2K7 antikoerper, Map2k7 antikoerper, map2k7 antikoerper, map2k7.L antikoerper

Hintergrund: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

Molekulargewicht: 43 kDa

Gen-ID: 5609

NCBI Accession: NP_660186

UniProt: O14733

Pathways: MAPK Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling