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MAP2K7 Produkte

(Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Kategorien

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008].

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Ausgewählte MAP2K7 Kategorien

MAP2K7 Antikörper

High quality antibodies with extensive validation data.

MAP2K7 ELISA Kits

Reliable ELISA kits for a wide range of species.

MAP2K7 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MAP2K7 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC
Validierungen
  • (2)
  • (6)
Kat. Nr. ABIN969271
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (7)
Kat. Nr. ABIN3023157
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p), PLA
Validierungen
  • (5)
Kat. Nr. ABIN562438
Menge 100 μg
Datenblatt Datenblatt

Empfohlene MAP2K7 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968653
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968652
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380778
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene MAP2K7 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN5569656
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect cells (Sf21)
Validierungen
  • (2)
Kat. Nr. ABIN5569657
Menge 5 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN5570681
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MAP2K7 Produkten

Zhang, Wang, Man, Zhu, Bai, Wei, Liu, Liu, Wang, Gu, Wang: "Reactive oxygen species generated from skeletal muscles are required for gecko tail regeneration." in: Scientific reports, Vol. 6, pp. 20752, (2017) (PubMed).

Samak, Chaudhry, Gangwar, Narayanan, Jaggar, Rao: "Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium." in: The Biochemical journal, Vol. 465, Issue 3, pp. 503-15, (2015) (PubMed).

Nakagawa, Sugahara, Yamasaki, Kajiho, Takahashi, Hirayama, Minami, Ohta, Watanabe, Hata, Katada, Nishina: "Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation." in: The Biochemical journal, Vol. 427, Issue 2, pp. 237-45, (2010) (PubMed).

Yoshizawa, Hammaker, Sweeney, Boyle, Firestein: "Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3252-8, (2008) (PubMed).

Sundarrajan, Boyle, Chabaud-Riou, Hammaker, Firestein: "Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK." in: Arthritis and rheumatism, Vol. 48, Issue 9, pp. 2450-60, (2003) (PubMed).

Kawaguchi, Onuchic, Huang: "Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15229-32, (2002) (PubMed).

Yang: "Mixed lineage kinase ZAK utilizing MKK7 and not MKK4 to activate the c-Jun N-terminal kinase and playing a role in the cell arrest." in: Biochemical and biophysical research communications, Vol. 297, Issue 1, pp. 105-10, (2002) (PubMed).

Synonyme und alternative Namen zu MAP2K7

mitogen-activated protein kinase kinase 7 (MAP2K7), mitogen activated protein kinase kinase 7 (Map2k7), mitogen-activated protein kinase kinase 7 (Map2k7), mitogen-activated protein kinase kinase 7 (map2k7), mitogen-activated protein kinase kinase 7 L homeolog (map2k7.L), 2, 5930412N11Rik, JNKK, Jnkk2, JNKK 2, MAP2K7, map2k7-A, Mapkk7, MAPKK7, MAPKK 7, Mek7, MEK 7, Mkk7, MKK7, PRKMK7, Prkmk7, SAPKK-4, SAPKK4, sek2, si:ch211-254d18.2

Bezeichner auf Proteinebene für MAP2K7

  • mitogen-activated protein kinase kinase 7
  • JNK kinase 2
  • JNK-activating kinase 2
  • JNKK 2
  • MAP kinase kinase 7
  • MAPK/ERK kinase 7
  • MAPKK 7
  • MEK 7
  • c-Jun N-terminal kinase kinase 2
  • dual specificity mitogen-activated protein kinase kinase 7
  • SAPK kinase 4
  • stress-activated protein kinase kinase 4
  • mitogen activated protein kinase kinase 7
  • protein kinase, mitogen activated, kinase 7
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