NFKB1 Antikörper (AA 432-499)

Produktnummer ABIN2467863

Produktdetails anti-NFKB1 Antikörper

Target: NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))

Bindungsspezifität: AA 432-499

Reaktivität: Human, Maus, Ratte

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser NFKB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity-purified

Anwendungsinformationen

Applikationshinweise: NFkB antibody can be used for the detection of NFkB by Western blot, may also work for IHC and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Konservierungsmittel: Without preservative

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: NFKB1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Details zu NFKB1

Target: NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))

Andere Bezeichnung: NFKB1 (NFKB1 Produkte)

Synonyme: GKLP antikoerper, NKTL antikoerper, NTKL antikoerper, P105 antikoerper, TAPK antikoerper, TEIF antikoerper, TRAP antikoerper, EBP-1 antikoerper, KBF1 antikoerper, NF-kB1 antikoerper, NF-kappa-B antikoerper, NF-kappaB antikoerper, NFKB-p105 antikoerper, NFKB-p50 antikoerper, NFkappaB antikoerper, p105 antikoerper, p50 antikoerper, NF-kB antikoerper, NF-KB1 antikoerper, ebp-1 antikoerper, kbf1 antikoerper, nf-kappa-b antikoerper, nf-kappaB antikoerper, nfkb-p105 antikoerper, nfkb-p50 antikoerper, NF-kappaB1 antikoerper, p50/p105 antikoerper, BICDR-1 antikoerper, bicdr1 antikoerper, ccdc64 antikoerper, SCY1 like pseudokinase 1 antikoerper, nuclear factor kappa B subunit 1 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antikoerper, nuclear factor NF-kappa-B p105 subunit antikoerper, nucleoporin 107 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antikoerper, SCYL1 antikoerper, NFKB1 antikoerper, Nfkb1 antikoerper, nfkb1.L antikoerper, CpipJ_CPIJ012236 antikoerper, Nup107 antikoerper, nfkb1 antikoerper

Hintergrund: Nuclear factor κ,-B DNA binding subunit, Nuclear factor of κ, light chain gene enhancer in B-cells 1 (p105). NFκ,B has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFκ,B is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ,-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ,-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

Molekulargewicht: 105.4 kDa (calculated)

Gen-ID: 4790

NCBI Accession: NP_003989

UniProt: P19838

Pathways: p53 Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteine