IL-1 beta Antikörper (AA 109-251)

Produktnummer ABIN2116858

Produktdetails anti-IL-1 beta Antikörper

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Bindungsspezifität: AA 109-251

Reaktivität: Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-1 beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Polyclonal Antibody to Interleukin 1 Beta (IL1b)

Sequenz: MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- IK PRSAHYSFQS NVKYNFMRVI HQECILNDAL NQSIIRDMSG PYLTATTLNN LEEAVKFDMV AYVSEEDSQL PVTLRISKTQ LFVSAQNEDE PVLLKEMPET PKIIKDETNL LFFWEKHGSM DYFKSVAHPK LFIATKQEKL V

Spezifität: The antibody is a rabbit polyclonal antibody raised against IL1b. It has been selected for its ability to recognize IL1b in immunohistochemical staining and western blotting.

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Interleukin 1 Beta (IL1b) corresdonding to Ile109~Val251 (Accession # P08831)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western blotting: 0.5-2 μg/mL

1:450-1800 Immunohistochemistry: 5-20 μg/mL

1:45-180 Immunocytochemistry: 5-20 μg/mL

1:45-180 Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze/thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Details zu IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Andere Bezeichnung: Interleukin 1 Beta (IL1B Produkte)

Synonyme: IL-1 antikoerper, IL1-BETA antikoerper, IL1F2 antikoerper, IL-1BETA antikoerper, IL1beta antikoerper, il1-b antikoerper, zgc:111873 antikoerper, IL-1B antikoerper, IL-1beta antikoerper, Il-1b antikoerper, IL1B antikoerper, IL-1 beta antikoerper, IL-1b antikoerper, interleukin 1 beta antikoerper, interleukin 1, beta antikoerper, IL1B antikoerper, il1b antikoerper, Il1b antikoerper

Hintergrund: IL1-B, IL1-Beta, IL1F2, IL-1β, Interleukin-1 Family Member 2, Catabolin

Pathways: NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome