IL-1 beta Antikörper

Produktnummer ABIN120889

Produktdetails anti-IL-1 beta Antikörper

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reaktivität: Schaf, Rind (Kuh), Ziege

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-1 beta Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Purified

Immunogen: Recombinant ovine IL-1 Beta

Klon: 1D4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 5 μg/mL as coating antibody. Flow Cytometry: 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Andere Bezeichnung: Interleukin-1 beta / IL-1B (IL1B Produkte)

Synonyme: IL-1 antikoerper, IL1-BETA antikoerper, IL1F2 antikoerper, IL-1BETA antikoerper, IL1beta antikoerper, il1-b antikoerper, zgc:111873 antikoerper, IL-1B antikoerper, IL-1beta antikoerper, Il-1b antikoerper, IL1B antikoerper, IL-1 beta antikoerper, IL-1b antikoerper, interleukin 1 beta antikoerper, interleukin 1, beta antikoerper, IL1B antikoerper, il1b antikoerper, Il1b antikoerper

Hintergrund: Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2

Pathways: NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome