anti-Human TICAM1 Antikörper für Western Blotting
Recommended TICAM1 Antibody (geliefert von: Anmelden zum Anzeigen )
- Antigen
-
Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Antikörper
Synonyme für dieses Antigen anzeigen- IIAE6
- MyD88-3
- PRVTIRB
- TICAM-1
- TRIF
- AW046014
- AW547018
- trif
- toll like receptor adaptor molecule 1
- toll-like receptor adaptor molecule 1
- TICAM1
- Ticam1
- ticam1
- Reaktivität
-
Maus, Ratte (Rattus), Human
Alternativen - Wirt
-
Kaninchen
Alternativen - Klonalität
- Konjugat
-
Dieser TICAM1 Antikörper ist unkonjugiert
Alternativen - Applikation
-
Immunohistochemistry (IHC), Western Blotting (WB)
Alternativen - Optionen
- Hersteller
- Anmelden zum Anzeigen
- Hersteller Produkt- Nr.
- Anmelden zum Anzeigen
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Bilder
Produktnummer ABIN3021572
$ 393.25
Zzgl. Versandkosten $45.00
Zzgl. Versandkosten $45.00
| Relevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 20.811132 | ABIN266066 | ICC IF IP SimWes WB | Rabbit | Internal Region | Anmelden zum Anzeigen | Polyclonal | 26 | |||
| 19.132376 | ABIN2855929 | ICC IF WB | Rabbit | IgG | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 16.750505 | ABIN1871543 | ICC IHC WB | Rabbit | IgG | AA 443-685 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 16.750505 | ABIN1875095 | IHC WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 16.750505 | ABIN2903154 | IF/ICC IHC IP WB | Rabbit | AA 443-685 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 15.250505 | ABIN3044491 | IHC (fro) IHC (p) WB | Rabbit | IgG | AA 692-712, C-Term | Anmelden zum Anzeigen | Polyclonal | 1 | ||
| 13.750505 | ABIN6265566 | ELISA IHC WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 12.38187 | ABIN2613488 | ELISA WB | Goat | Internal Region | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 12.38187 | ABIN4902391 | ELISA WB | Rabbit | IgG | AA 663-712 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 12.38187 | ABIN6149149 | WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 0 | ||||
| 12.250505 | ABIN541214 | IHC (p) WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 3 | ||||
| 10.750505 | ABIN3029185 | IHC (fro) IHC (p) WB | Rabbit | Ig Fraction | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 10 | ABIN213993 | IHC IHC (p) WB | Rabbit | IgG | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 10 | ABIN6292306 | IHC WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 9.250505 | ABIN1881885 | WB | Rabbit | AA 115-143, N-Term | Anmelden zum Anzeigen | Polyclonal | 5 | |||
| 9.250505 | ABIN537469 | WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 3 | ||||
| 7.750506 | ABIN3223003 | IHC WB | Rabbit | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 7.750506 | ABIN1030771 | IHC ELISA WB | Rabbit | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 7 | ABIN457458 | IHC IHC (p) WB | Rabbit | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 7 | ABIN1490877 | WB | Mouse | IgG1 | AA 120-420 | Anmelden zum Anzeigen | 1G7 | 0 |
General |
|
|---|---|
| Antigen | Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Antikörper |
| Reaktivität | Maus, Ratte (Rattus), Human Alternativen |
| Wirt | Kaninchen Alternativen |
| Klonalität | |
| Konjugat | Dieser TICAM1 Antikörper ist unkonjugiert Alternativen |
| Applikation |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternativen
|
|
1 Publikation vorhanden |
| Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-TICAM1 AntikörperTarget Details TICAM1 Anwendungsinformationen Handhabung Referenzen für anti-TICAM1 Antikörper (ABIN3021572) Bilder |
|
| Reinigung | Affinity purification |
| Immunogen | Recombinant protein of human TICAM1 |
| Isotyp | IgG |
| Plasmids, Primers & others | |
Target Details TICAM1Produktdetails anti-TICAM1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TICAM1 Antikörper (ABIN3021572) Bilder zurück nach oben |
|
| Antigen | |
| Andere Bezeichnung | TICAM1 (TICAM1 Antibody Abstract) |
| Hintergrund |
Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 AAs known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated activator of interferon), and TRAM (Toll-receptor-associated molecule). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IkappaB that normally maintains NF-kappaB inactivity by sequestering it in the cytoplasm. TRIF (also termed TICAM-1) is a TIR-domain adaptor protein described to activate NF-kappaB, IRF3 and trigger IFN-beta production. Studies using dominant negative forms of TRIF and siRNA targeting TRIF show that TRIF functions downstream of both TLR3 and TLR4 in response to dsRNA and LPS respectively. TRIF recruits TRAF6-TAK1-TAB2 to the receptor complex which leads to NF-kappaB activation. In addition, TRIF can trigger signaling of that lead to the induction of apoptosis. Synonyms: TRIF, PRVTIRB, TICAM-1 |
| Gen-ID | 148022 |
| UniProt | Q8IUC6 |
| Pathways | TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades |
AnwendungsinformationenProduktdetails anti-TICAM1 Antikörper Target Details TICAM1 Handhabung Referenzen für anti-TICAM1 Antikörper (ABIN3021572) Bilder zurück nach oben |
|
| Applikations-hinweise | Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200 |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-TICAM1 Antikörper Target Details TICAM1 Anwendungsinformationen Referenzen für anti-TICAM1 Antikörper (ABIN3021572) Bilder zurück nach oben |
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| Format | Liquid |
| Buffer | PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3 |
| Konservierungs-mittel | Sodium azide |
| Vorsichtsmaßnahmen | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Handhabung | Avoid freeze / thaw cycles |
| Lagerung | -20 °C/-80 °C |
Referenzen für anti-TICAM1 Antikörper (ABIN3021572)Produktdetails anti-TICAM1 Antikörper Target Details TICAM1 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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| Produkt verwendet in: |
Du, Qiao, Chen, Chen, Liu, Lin, Wang, Xie: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) |
BilderProduktdetails anti-TICAM1 Antikörper Target Details TICAM1 Anwendungsinformationen Handhabung Referenzen für anti-TICAM1 Antikörper (ABIN3021572) zurück nach oben |
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| Bilder des Herstellers |
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) antibody
Western blot analysis of extracts of various cell lines, using TICAM1 antibody.
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