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TICAM1 Antikörper (C-Term)

TICAM1 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855929
  • Target Alle TICAM1 Antikörper anzeigen
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Bindungsspezifität
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 26
    • 11
    • 3
    • 2
    Human
    Wirt
    • 23
    • 4
    • 3
    Kaninchen
    Klonalität
    • 25
    • 5
    Polyklonal
    Konjugat
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TICAM1 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit polyclonal antibody to TRIF (toll-like receptor adaptor molecule 1)
    TRIF antibody [C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRIF. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product TICAM1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HeLa

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.01 mg/mL
    Buffer
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Mlcochova, Winstone, Zuliani-Alvarez, Gupta: "TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages." in: Cell reports, Vol. 30, Issue 12, pp. 3972-3980.e5, (2020) (PubMed).

  • Target
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Andere Bezeichnung
    toll like receptor adaptor molecule 1 (TICAM1 Produkte)
    Synonyme
    IIAE6 antikoerper, MyD88-3 antikoerper, PRVTIRB antikoerper, TICAM-1 antikoerper, TRIF antikoerper, AW046014 antikoerper, AW547018 antikoerper, trif antikoerper, toll like receptor adaptor molecule 1 antikoerper, toll-like receptor adaptor molecule 1 antikoerper, TICAM1 antikoerper, Ticam1 antikoerper, ticam1 antikoerper
    Hintergrund
    TRIF, or TICAM1, is a Toll/IL1R (MIM 147810) (TIR) domain-containing adaptor molecule, like MYD88 (MIM 602170) and TIRAP (MIM 606252), that induces interferon-beta (IFNB, MIM 147640), specifically interacts with TLR3 (MIM 603029), and activates nuclear factor kappa-B (NFKB, see MIM 164011).[supplied by OMIM]

    Molekulargewicht
    76 kDa
    Gen-ID
    148022
    UniProt
    Q8IUC6
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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