anti-Human TICAM1 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended TICAM1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Antikörper
  • IIAE6
  • MyD88-3
  • PRVTIRB
  • TICAM-1
  • TRIF
  • AW046014
  • AW547018
  • trif
  • toll like receptor adaptor molecule 1
  • toll-like receptor adaptor molecule 1
  • TICAM1
  • Ticam1
  • ticam1
Epitop
AA 692-712, C-Term
25
5
5
4
4
3
2
2
2
2
2
2
1
1
1
1
Reaktivität
Human
80
31
15
5
4
2
2
Wirt
Kaninchen
73
8
8
Klonalität
Polyklonal
Konjugat
Dieser TICAM1 Antikörper ist unkonjugiert
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
82
30
18
16
13
8
8
4
3
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN3044491
$ 280.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2629165 IHC IHC (fro) IHC (p) WB Rabbit IgG AA 692-712 Anmelden zum Anzeigen Polyclonal 0
1 ABIN3029185 IHC (fro) IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN187923 IHC (fro) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Antikörper
Epitop AA 692-712, C-Term
(25), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Human
(80), (31), (15), (5), (4), (2), (2)
Wirt Kaninchen
(73), (8), (8)
Klonalität
Polyklonal
Konjugat Dieser TICAM1 Antikörper ist unkonjugiert
(1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(82), (30), (18), (16), (13), (8), (8), (4), (3), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TICAM1 Antikörper

Target Details TICAM1 Anwendungsinformationen Handhabung Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for TIR domain-containing adapter molecule 1(TICAM1) detection. Tested with WB, IHC-P, IHC-F in Human.
Sequenz NNHMWNQRGS QAPEDKTQEA E
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for TIR domain-containing adapter molecule 1(TICAM1) detection. Tested with WB, IHC-P, IHC-F in Human.
Gene Name: toll-like receptor adaptor molecule 1
Protein Name: TIR domain-containing adapter molecule 1
Reinigung Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human TRIF(692-712aa NNHMWNQRGSQAPEDKTQEAE).
Isotyp IgG
Plasmids, Primers & others

Target Details TICAM1

Produktdetails anti-TICAM1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TICAM1 (TICAM1 Antibody Abstract)
Hintergrund TICAM(TIR DOMAIN-CONTAINING ADAPTOR MOLECULE 1), also known as TICAM1 or TRIF, is an adapter in responding to activation of toll-like receptors(TLRs). It mediates the rather delayed cascade of two TLR-associated signaling cascades, where the other one is dependent upon a MyD88 adapter. By genomic sequence analysis, Oshiumi et al.(2003) mapped the TICAM1 gene to chromosome 19p13.3. By coimmunoprecipitation analysis, Oshiumi et al.(2003) showed that TICAM1 interacts specifically with TLR3, but not with other TLRs. Functional analysis showed that the association of TLR3 and TICAM1 mediates dsRNA activation of IFNB, through either NFKB, AP1, or IRF3. TICAM1 activation of NFKB was found to occur predominantly through IRAK1 rather than IRAK2. Small interfering(si)RNA blockage of TICAM1, just upstream of the TIR domain, reduced IFNB production in response to dsRNA.

Synonyms: HSD34 antibody|MGC35334 antibody|Proline rich vinculin and TIR domain containing protein B antibody|Proline-rich antibody|PRVTIRB antibody|Putative NF kappa B activating protein 502H antibody|Putative NF-kappa-B-activating protein 502H antibody|Putative NFkB activating protein antibody|Ring finger protein 36 antibody|RNF36 antibody|TCAM1_HUMAN antibody|TICAM 1 antibody|TICAM-1 antibody|TICAM1 antibody|TIR domain containing adapter molecule 1 antibody|TIR domain containing adapter protein inducing IFN beta antibody|TIR domain containing adaptor inducing interferon beta antibody|TIR domain-containing adapter molecule 1 antibody|TIR domain-containing adapter protein inducing IFN-beta antibody|Toll interleukin 1 receptor domain containing adapter protein inducing interferon beta antibody|Toll like receptor adaptor molecule 1 antibody|Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta antibody|TRIF antibody|TRIF protein antibody|TRIM 69 antibody|TRIM69 antibody|Trimless antibody|Tripartite motif containing 69 antibody|vinculin and TIR domain-containing protein B antibody
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TICAM1 Antikörper Target Details TICAM1 Handhabung Bilder zurück nach oben
Applikations-hinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TICAM1 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TICAM1 Antikörper Target Details TICAM1 Anwendungsinformationen Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungs-mittel Thimerosal (Merthiolate), Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Haltbarkeit 12 months

Bilder

Produktdetails anti-TICAM1 Antikörper Target Details TICAM1 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (AA 692-712), (C-Term) antibody (ABIN3044491) Anti-TRIF antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue
Western Blotting (WB) image for anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (AA 692-712), (C-Term) antibody (ABIN3044491) Anti-TRIF antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: HL-60 Cell Ly...
Western Blotting (WB) image for anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (AA 692-712), (C-Term) antibody (ABIN3044491) Lane 4: Recombinant Human TICAM1 Protein 1.25ng