anti-Human CD14 Antikörper für Enzyme Immunoassay

Recommended CD14 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD14 Molecule (CD14) Antikörper
  • CD14 molecule
  • CD14 antigen
  • CD14
  • Cd14
Reaktivität
Human
1049
163
117
104
100
99
81
73
72
65
59
52
42
40
36
27
17
17
15
13
9
9
7
3
2
1
1
1
Wirt
Maus
982
142
70
24
3
Klonalität
Monoklonal
Konjugat
Dieser CD14 Antikörper ist unkonjugiert
109
106
80
73
36
27
27
23
20
20
15
15
15
15
15
10
10
10
9
8
8
8
7
7
7
6
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
970
346
289
241
222
147
82
69
60
52
26
17
14
13
11
8
6
4
3
3
3
3
3
2
2
2
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN1105871
$ 286.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN118509 EIA FACS WB Mouse IgG2a Anmelden zum Anzeigen Tük4 6
1 ABIN118510 EIA FACS WB Mouse IgG2a Anmelden zum Anzeigen Tük4 6
1 ABIN614903 EIA IHC (p) WB Goat Anmelden zum Anzeigen Polyclonal 0
1 ABIN5553166 EIA IHC (p) WB Goat Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN5552159 EIA IHC (p) WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5552160 EIA IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN1105869 EIA IHC (p) Mouse IgG1 Anmelden zum Anzeigen 5A3 2
1 ABIN319672 EIA FACS Mouse IgG2a Anmelden zum Anzeigen Tük4 5
1 ABIN118508 EIA Func FACS WB Mouse IgG2a Anmelden zum Anzeigen Tük4 5
1 ABIN120558 EIA Func FACS IP WB Mouse IgG1 Anmelden zum Anzeigen MEM-18 2
1 ABIN126002 EIA Func FACS IP WB Mouse IgG1 Anmelden zum Anzeigen MEM-18 0

General

Antigen CD14 Molecule (CD14) Antikörper
Reaktivität Human
(1049), (163), (117), (104), (100), (99), (81), (73), (72), (65), (59), (52), (42), (40), (36), (27), (17), (17), (15), (13), (9), (9), (7), (3), (2), (1), (1), (1)
Wirt Maus
(982), (142), (70), (24), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD14 Antikörper ist unkonjugiert
(109), (106), (80), (73), (36), (27), (27), (23), (20), (20), (15), (15), (15), (15), (15), (10), (10), (10), (9), (8), (8), (8), (7), (7), (7), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(970), (346), (289), (241), (222), (147), (82), (69), (60), (52), (26), (17), (14), (13), (11), (8), (6), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 10 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD14 Antikörper

Target Details CD14 Anwendungsinformationen Handhabung Referenzen für anti-CD14 Antikörper (ABIN1105871) Bilder
Spezifität Recognises the lipopolysaccharide receptor (LPS R), a 55 kDa protein.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Ion Exchange Chromatography
Immunogen Monocytes.
Klon B-A8
Isotyp IgG1
Plasmids, Primers & others

Target Details CD14

Produktdetails anti-CD14 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CD14 Antikörper (ABIN1105871) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD14 (CD14 Antibody Abstract)
Hintergrund CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
Gen-ID 929
NCBI Accession NP_000582
UniProt P08571
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-CD14 Antikörper Target Details CD14 Handhabung Referenzen für anti-CD14 Antikörper (ABIN1105871) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CD14 Antikörper Target Details CD14 Anwendungsinformationen Referenzen für anti-CD14 Antikörper (ABIN1105871) Bilder zurück nach oben
Format Liquid
Buffer PBS containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.

Referenzen für anti-CD14 Antikörper (ABIN1105871)

Produktdetails anti-CD14 Antikörper Target Details CD14 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lødrup Carlsen, Granum: "Soluble CD14: role in atopic disease and recurrent infections, including otitis media." in: Current allergy and asthma reports, Vol. 7, Issue 6, pp. 436-43, 2007

Yates, Rovis, Mitchell, Afzali, Tsang, Garin, Lechler, Lombardi, Garden: "The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro." in: International immunology, Vol. 19, Issue 6, pp. 785-99, 2007

Asai, Makimura, Kawabata, Ogawa: "Soluble CD14 discriminates slight structural differences between lipid as that lead to distinct host cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 11, pp. 7674-83, 2007

Dalwadi, Krysan, Heuze-Vourch, Dohadwala, Elashoff, Sharma, Cacalano, Lichtenstein, Dubinett: "Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 21, pp. 7674-82, 2005

Kuusniemi, Lapatto, Holmberg, Karikoski, Rapola, Jalanko: "Kidneys with heavy proteinuria show fibrosis, inflammation, and oxidative stress, but no tubular phenotypic change." in: Kidney international, Vol. 68, Issue 1, pp. 121-32, 2005

Fernández-Real, Broch, Richart, Vendrell, López-Bermejo, Ricart: "CD14 monocyte receptor, involved in the inflammatory cascade, and insulin sensitivity." in: The Journal of clinical endocrinology and metabolism, Vol. 88, Issue 4, pp. 1780-4, 2003

Wiendl, Mitsdoerffer, Schneider, Melms, Lochmuller, Hohlfeld, Weller: "Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies." in: Brain : a journal of neurology, Vol. 126, Issue Pt 5, pp. 1026-35, 2003

von Wolff, Stieger, Lumpp, Bücking, Strowitzki, Thaler: "Endometrial interleukin-6 in vitro is not regulated directly by female steroid hormones, but by pro-inflammatory cytokines and hypoxia." in: Molecular human reproduction, Vol. 8, Issue 12, pp. 1096-102, 2002

Juan, Hailman, Kelley, Wright, Lichenstein: "Identification of a domain in soluble CD14 essential for lipopolysaccharide (LPS) signaling but not LPS binding." in: The Journal of biological chemistry, Vol. 270, Issue 29, pp. 17237-42, 1995

Goyert, Ferrero, Rettig, Yenamandra, Obata, Le Beau: "The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors." in: Science (New York, N.Y.), Vol. 239, Issue 4839, pp. 497-500, 1988

Bilder

Produktdetails anti-CD14 Antikörper Target Details CD14 Anwendungsinformationen Handhabung Referenzen für anti-CD14 Antikörper (ABIN1105871) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-CD14 Molecule (CD14) antibody (ABIN1105871) anti-CD14 Molecule (CD14) antibody