anti-Human CD14 Antikörper für Blocking Reagent

Recommended CD14 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD14 Molecule (CD14) Antikörper
  • CD14 molecule
  • CD14 antigen
  • CD14
  • Cd14
Reaktivität
Human
1076
159
117
104
100
99
81
73
72
65
59
52
44
41
36
27
21
17
15
13
9
9
7
4
3
1
1
1
Wirt
Maus
1010
141
67
24
3
Klonalität
Monoklonal
Konjugat
Dieser CD14 Antikörper ist konjugiert mit PerCP-Cy5.5
112
108
81
75
37
27
27
22
20
20
15
15
15
15
15
12
10
10
9
8
8
8
7
7
7
6
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP)
975
345
286
237
227
145
84
69
60
52
26
17
14
13
12
8
5
4
3
3
3
3
3
3
2
2
2
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2660275
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN206948 BR ELISA FACS Func IP Neut WB Mouse IgG1 AA 57-64 Anmelden zum Anzeigen MEM-18 0
1 ABIN1967146 BR ELISA FACS Func IP Neut WB Mouse IgG1 Anmelden zum Anzeigen MEM-18 0
1 ABIN2660276 BR FACS IP PerCP-Cy5.5 Mouse IgG2a kappa Anmelden zum Anzeigen M5E2 6
1 ABIN1967084 BR FACS Mouse IgG1 Anmelden zum Anzeigen hCD4 0

General

Antigen CD14 Molecule (CD14) Antikörper
Reaktivität Human
(1076), (159), (117), (104), (100), (99), (81), (73), (72), (65), (59), (52), (44), (41), (36), (27), (21), (17), (15), (13), (9), (9), (7), (4), (3), (1), (1), (1)
Wirt Maus
(1010), (141), (67), (24), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD14 Antikörper ist konjugiert mit PerCP-Cy5.5
(112), (108), (81), (75), (37), (27), (27), (22), (20), (20), (15), (15), (15), (15), (15), (12), (10), (10), (9), (8), (8), (8), (7), (7), (7), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP)
(975), (345), (286), (237), (227), (145), (84), (69), (60), (52), (26), (17), (14), (13), (12), (8), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD14 Antikörper

Target Details CD14 Anwendungsinformationen Handhabung Referenzen für anti-CD14 Antikörper (ABIN2660275) Bilder
Kreuzreaktivität Schimpanse, Cynomolgus, Rhesusaffen, Capuchin Monkey, Saguinus oedipus, Pigtailed Macaque, Marmoset, Squirrel Monkey (Saimiri spec.), Rind (Kuh), Schwein, Hund
Reinigung The antibody was purified by affinity chromatography, and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
Klon M5E2
Isotyp IgG2a kappa
Plasmids, Primers & others

Target Details CD14

Produktdetails anti-CD14 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CD14 Antikörper (ABIN2660275) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD14 (CD14 Antibody Abstract)
Hintergrund CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-CD14 Antikörper Target Details CD14 Handhabung Referenzen für anti-CD14 Antikörper (ABIN2660275) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CD14 Antikörper Target Details CD14 Anwendungsinformationen Referenzen für anti-CD14 Antikörper (ABIN2660275) Bilder zurück nach oben
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-CD14 Antikörper (ABIN2660275)

Produktdetails anti-CD14 Antikörper Target Details CD14 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Santos, Bárcia, Simões, Gaspar, Calado, Agua-Doce, Almeida, Almeida, Filipe, Teixeira, Martins, Graça, Cruz, Cruz, Cruz: "The role of human umbilical cord tissue-derived mesenchymal stromal cells (UCX®) in the treatment of inflammatory arthritis." in: Journal of translational medicine, Vol. 11, pp. 18, 2013

Iwamoto, Iwai, Tsujiyama, Kurahashi, Takeshita, Naoe, Masunaga, Ogawa, Oguchi, Miyazaki: "TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 3, pp. 1449-57, 2007

Power, Wang, Manning, Kell, Aherne, Aherne, Wu, Redmond: "Bacterial lipoprotein delays apoptosis in human neutrophils through inhibition of caspase-3 activity: regulatory roles for CD14 and TLR-2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 8, pp. 5229-37, 2004

Williams, Corey, Westmoreland, Pauley, Knight, deBakker, Alvarez, Lackner: "Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS." in: The Journal of experimental medicine, Vol. 193, Issue 8, pp. 905-15, 2001

Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000

Stocks, Albrechtsen, Kerr: "Expression of the CD15 differentiation antigen (3-fucosyl-N-acetyl-lactosamine, LeX) on putative neutrophil adhesion molecules CR3 and NCA-160." in: The Biochemical journal, Vol. 268, Issue 2, pp. 275-80, 1990

Bilder

Produktdetails anti-CD14 Antikörper Target Details CD14 Anwendungsinformationen Handhabung Referenzen für anti-CD14 Antikörper (ABIN2660275) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-CD14 Molecule (CD14) antibody (PerCP-Cy5.5) (ABIN2660275) anti-CD14 Molecule (CD14) antibody (PerCP-Cy5.5)