Sclerostin Protein (SOST) (His tag)

Produktnummer ABIN7535941

Produktdetails

Target: Sclerostin (SOST)

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Sclerostin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Rat Sclerostin/SOST Protein

Sequenz: FKNDATEIIP GLREYPEPPQ ELENNQTMNR AENGGRPPHH PYDTKDVSEY SCRELHYTRF VTDGPCRSAK PVTELVCSGQ CGPARLLPNA IGRVKWWRPN GPDFRCIPDR YRAQRVQLLC PGGAAPRSRK VRLVASCKCK RLTRFHNQSE LKDFGPETAR PQKGRKPRPR ARGAKANQAE LENAY

Spezifität: Phe29-Tyr213

Reinheit: > 95 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <0.1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: Sclerostin (SOST)

Andere Bezeichnung: Sclerostin/SOST (SOST Produkte)

Synonyme: LOC100313724 Protein, CDD Protein, VBCH Protein, 5430411E23Rik Protein, sclerostin Protein, LOC100313724 Protein, SOST Protein, Sost Protein

Hintergrund:

Description: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Name: sclerostin,SOST,VBCH,SOST

Gen-ID: 80722

UniProt: Q99P67