Sclerostin Produkte
(Sclerostin (SOST))
Kategorien
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008].
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Ausgewählte Sclerostin Kategorien
Sclerostin Antikörper
High quality antibodies with extensive validation data.
Sclerostin ELISA Kits
Reliable ELISA kits for a wide range of species.
Sclerostin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Sclerostin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN390193
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN7435190
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7168635
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Sclerostin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6959272
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6959273
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6959274
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Sclerostin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275636
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275637
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275635
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Sclerostin Produkten
: "Targeting SOST using a small-molecule compound retards breast cancer bone metastasis." in: Molecular cancer, Vol. 21, Issue 1, pp. 228, (2023) (PubMed).: "Significance of acPWV for Survival of Hemodialysis Patients." in: Medicina (Kaunas, Lithuania), Vol. 56, Issue 9, (2020) (PubMed).
: "Evaluation of serum fibroblast growth factor-23 in patients with axial spondyloarthritis and its association with sclerostin, inflammation, and spinal damage." in: Rheumatology international, Vol. 39, Issue 5, pp. 835-840, (2020) (PubMed).
: "Role of sclerostin and dkk1 in bone remodeling in type 2 diabetic patients." in: Endocrine research, Vol. 43, Issue 1, pp. 29-38, (2018) (PubMed).
: "Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips." in: Calcified tissue international, Vol. 100, Issue 6, pp. 609-618, (2018) (PubMed).
: "The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism." in: European journal of pharmacology, Vol. 824, pp. 115-119, (2018) (PubMed).
: "Sclerostin Promotes Bone Remodeling in the Process of Tooth Movement." in: PLoS ONE, Vol. 12, Issue 1, pp. e0167312, (2017) (PubMed).
: "Upregulated serum sclerostin level in the T2DM patients with femur fracture inhibits the expression of bone formation/remodeling-associated biomarkers via antagonizing Wnt signaling." in: European review for medical and pharmacological sciences, Vol. 21, Issue 3, pp. 470-478, (2017) (PubMed).
: "DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 2, pp. 635-52, (2016) (PubMed).
: "Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 10, pp. 1791-1802, (2016) (PubMed).
Synonyme und alternative Namen zu Sclerostin
sclerostin (LOC100313724), sclerostin (SOST), sclerostin (Sost), 5430411E23Rik, CDD, LOC100313724, VBCHBezeichner auf Proteinebene für Sclerostin
- sclerostin
- sclerosteosis
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