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SCN1B Produkte

(Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Kategorien

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

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Ausgewählte SCN1B Kategorien

SCN1B Antikörper

High quality antibodies with extensive validation data.

SCN1B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SCN1B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, FACS, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN654602
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7169933
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, FACS, IHC (p), EIA
Validierungen
  • (3)
Kat. Nr. ABIN954692
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene SCN1B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319273
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rabbit
Source Yeast
Validierungen
Kat. Nr. ABIN1473305
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Cow
Source Yeast
Validierungen
Kat. Nr. ABIN1619654
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SCN1B Produkten

Baroni, Picco, Barbieri, Moran: "Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 106, Issue 1, pp. 13-29, (2014) (PubMed).

Barbieri, Baroni, Moran: "Identification of an intra-molecular disulfide bond in the sodium channel ?1-subunit." in: Biochemical and biophysical research communications, Vol. 420, Issue 2, pp. 364-7, (2012) (PubMed).

Chen, Westenbroek, Xu, Edwards, Sorenson, Chen, McEwen, OMalley, Bharucha, Meadows, Knudsen, Vilaythong, Noebels, Saunders, Scheuer, Shrager, Catterall, Isom: "Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 16, pp. 4030-42, (2004) (PubMed).

Synonyme und alternative Namen zu SCN1B

sodium channel, voltage-gated, type I, beta (Scn1b), sodium voltage-gated channel beta subunit 1 (Scn1b), sodium voltage-gated channel beta subunit 1 (SCN1B), GEFSP1

Bezeichner auf Proteinebene für SCN1B

  • sodium channel subunit beta-1
  • sodium channel, voltage-gated, type I, beta polypeptide
  • sodium channel voltage-gated type 1 beta polypeptide
  • sodium channel voltage-gated type I beta polypeptide
  • sodium channel, voltage-gated, type 1, beta polypeptide
  • sodium channel beta-1 subunit
  • sodium channel beta 1-subunit
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