Sclerostin Protein (SOST) (AA 69-258) (His tag)
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- Target Alle Sclerostin (SOST) Proteine anzeigen
- Sclerostin (SOST)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 69-258
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Spezies
- Cynomolgus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Sclerostin Protein ist gelabelt mit His tag.
- Verwendungszweck
- Cynomolgus SOST/Sclerostin Protein
- Sequenz
- Gln69-Tyr258
- Produktmerkmale
- Recombinant Cynomolgus SOST/Sclerostin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln69-Tyr258.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus SOST, His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product SOST Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Sclerostin (SOST)
- Andere Bezeichnung
- SOST (SOST Produkte)
- Synonyme
- LOC100313724 Protein, CDD Protein, VBCH Protein, 5430411E23Rik Protein, sclerostin Protein, LOC100313724 Protein, SOST Protein, Sost Protein
- Hintergrund
- SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
- Molekulargewicht
- 22.58 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- XP_005584428
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