GSK3 alpha Protein
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- Target Alle GSK3 alpha (GSK3a) Proteine anzeigen
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Verwendungszweck
- Recombinant Human GSK3α Protein
- Sequenz
- Ser97-Pro448
- Produktmerkmale
- A DNA sequence encoding the Human GSK3α Protein (P49840)(97-448)was expressed with a polyhistidine tag at the N-terminus.
- Reinheit
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GSK3a Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.5, 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- Andere Bezeichnung
- GSK3alpha (GSK3a Produkte)
- Synonyme
- 2700086H06Rik Protein, GSK3A Protein, GSK-3[a] Protein, GSK-3[b] Protein, GSK3 Protein, gsk3a Protein, xgsk3 Protein, glycogen synthase kinase 3 alpha Protein, glycogen synthase kinase 3 alpha b Protein, glycogen synthase kinase 3 alpha S homeolog Protein, GSK3A Protein, Gsk3a Protein, gsk3a Protein, gsk3ab Protein, gsk3a.S Protein, Bm1_31380 Protein
- Hintergrund
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Background: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1.
Synonym: Glycogen synthase kinase-3 alpha,GSK-3 alpha,Serine/threonine-protein kinase GSK3A ,GSK3A
- Molekulargewicht
- 39.4 kDa
- NCBI Accession
- NP_063937
- Pathways
- PI3K-Akt Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effekt
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