IL-6 Receptor Protein (His tag)
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- Target Alle IL-6 Receptor (IL6R) Proteine anzeigen
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL-6 Receptor Protein ist gelabelt mit His tag.
- Applikation
- ELISA
- Verwendungszweck
- Recombinant Human IL6R Protein with C-terminal 6xHis tag
- Spezifität
- IL6R (Leu20-Pro365) 6xHis tag
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- affinity purification
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Interleukin 6 Receptor (IL6R) (AA 229-468) protein (His-IF2DI Tag)
IL6R Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 6 Receptor (IL6R) (AA 21-120) protein (GST tag)IL6R Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 6 Receptor (IL6R) (AA 1-468) protein (GST tag)IL6R Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 6 Receptor (IL6R) (AA 20-365) protein (His tag)Crystallography grade IL6R Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 6 Receptor (IL6R) (AA 20-468) protein (rho-1D4 tag)Crystallography grade IL6R Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Konservierungsmittel
- Without preservative
- Lagerung
- -20 °C,-80 °C
- Haltbarkeit
- 12 months
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- Target
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Andere Bezeichnung
- IL6R (IL6R Produkte)
- Synonyme
- IL6R Protein, il-6ra Protein, CD126 Protein, IL-6R-1 Protein, IL-6RA Protein, IL6Q Protein, IL6RA Protein, IL6RQ Protein, gp80 Protein, IL6R1 Protein, Il6ra Protein, IL-6Ralpha Protein, IL-6R Protein, Il6r Protein, interleukin 6 receptor Protein, interleukin 6 receptor, alpha Protein, IL6R Protein, il6r Protein, Il6r Protein, Il6ra Protein
- Hintergrund
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Synonymes: CD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ
Description: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. - Molekulargewicht
- predicted molecular mass of 39.4 kDa after removal of the signal peptide.The apparent molecular mass of IL6R-His is 55-70 kDa due to glycosylation.
- Gen-ID
- 3570
- UniProt
- P08887
- Pathways
- JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints
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