IL-6 Receptor Produkte
(Interleukin 6 Receptor (IL6R))
Kategorien
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].
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Ausgewählte IL-6 Receptor Kategorien
IL-6 Receptor Antikörper
High quality antibodies with extensive validation data.
IL-6 Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
IL-6 Receptor Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IL-6 Receptor Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN7234279
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN3015522
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7434104
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene IL-6 Receptor ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN6720572
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
Kat. Nr.
ABIN6730982
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957177
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IL-6 Receptor Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN6964085
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123612
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307839
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IL-6 Receptor Produkten
: "Endothelial HuR deletion reduces the expression of proatherogenic molecules and attenuates atherosclerosis." in: International immunopharmacology, Vol. 65, pp. 248-255, (2018) (PubMed).: "The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma." in: Gene, Vol. 585, Issue 1, pp. 51-7, (2016) (PubMed).
: "Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, (2015) (PubMed).
: "Interleukin-6 and interleukin-6 receptor expression, localization, and involvement in pain-sensing neuron activation in a mouse intervertebral disc injury model." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 33, Issue 10, pp. 1508-14, (2015) (PubMed).
: "Establishment of a novel cell-based assay for screening small molecule antagonists of human interleukin-6 receptor." in: Acta pharmacologica Sinica, Vol. 35, Issue 11, pp. 1453-62, (2014) (PubMed).
: "Alterations of IL-6, IL-6R and gp130 in early and late onset severe preeclampsia." in: Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy, (2013) (PubMed).
: "Monoclonal anti-interleukin-6 receptor antibody attenuates donor-specific antibody responses in a mouse model of allosensitization." in: Transplant immunology, Vol. 28, Issue 2-3, pp. 138-43, (2013) (PubMed).
: "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models." in: Toxicology and applied pharmacology, Vol. 264, Issue 1, pp. 84-93, (2012) (PubMed).
: "Tumor necrosis factor-alpha (TNF-α)-blockade-induced hepatic sarcoidosis in psoriatic arthritis (PsA): case report and review of the literature." in: Clinical rheumatology, Vol. 30, Issue 1, pp. 133-7, (2011) (PubMed).
: "Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma." in: Annals of the New York Academy of Sciences, Vol. 1089, pp. 268-75, (2007) (PubMed).
Synonyme und alternative Namen zu IL-6 Receptor
interleukin 6 receptor (IL6R), interleukin 6 receptor (il6r), interleukin 6 receptor (Il6r), interleukin 6 receptor, alpha (Il6ra), CD126, gp80, IL-6R, IL-6R-1, il-6ra, IL-6RA, IL-6Ralpha, IL6Q, IL6R, Il6r, IL6R1, IL6RA, Il6ra, IL6RQBezeichner auf Proteinebene für IL-6 Receptor
- interleukin 6 receptor
- interleukin 6 receptor alpha
- interleukin-6 receptor subunit alpha
- CD126 antigen
- IL-6 receptor subunit alpha
- IL-6R 1
- membrane glycoprotein 80
- IL-6R subunit alpha
- IL-6R-alpha
- IL-6RA
- interleukin 6 receptor, alpha
- IL-6 receptor alpha chain
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