IL12A Produkte
(Interleukin 12 alpha (IL12A))
Kategorien
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].
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Ausgewählte IL12A Kategorien
IL12A Antikörper
High quality antibodies with extensive validation data.
IL12A ELISA Kits
Reliable ELISA kits for a wide range of species.
IL12A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IL12A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7430651
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7430654
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7428245
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene IL12A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (4)
Kat. Nr.
ABIN6730876
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Dog
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957001
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Horse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957003
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IL12A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5570078
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307676
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3081743
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IL12A Produkten
: "Regulatory T Cells and Their Derived Cytokine, Interleukin-35, Reduce Pain in Experimental Autoimmune Encephalomyelitis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 39, Issue 12, pp. 2326-2346, (2019) (PubMed).: "4,4'-diaponeurosporene, a C30 carotenoid, effectively activates dendritic cells via CD36 and NF-κB signaling in a ROS independent manner." in: Oncotarget, Vol. 7, Issue 27, pp. 40978-40991, (2018) (PubMed).
: "MiR674 inhibits the neuraminidase-stimulated immune response on dendritic cells via down-regulated Mbnl3." in: Oncotarget, Vol. 7, Issue 31, pp. 48978-48994, (2018) (PubMed).
: "Lycium barbarum Polysaccharide Promotes Maturation of Dendritic Cell via Notch Signaling and Strengthens Dendritic Cell Mediated T Lymphocyte Cytotoxicity on Colon Cancer Cell CT26-WT." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 2305683, (2018) (PubMed).
: "The effect of human placental chorionic villi derived mesenchymal stem cell on triple-negative breast cancer hallmarks." in: PLoS ONE, Vol. 13, Issue 11, pp. e0207593, (2018) (PubMed).
: "Modulation of the Tumor Microenvironment by CXCR4 Antagonist-Armed Viral Oncotherapy Enhances the Antitumor Efficacy of Dendritic Cell Vaccines against Neuroblastoma in Syngeneic Mice." in: Viruses, Vol. 10, Issue 9, (2018) (PubMed).
: "Effect of IL-17 in the development of colon cancer in mice." in: Oncology letters, Vol. 12, Issue 6, pp. 4929-4936, (2017) (PubMed).
: "Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy." in: Scientific reports, Vol. 6, pp. 24506, (2017) (PubMed).
: "H9N2 Avian Influenza Virus Protein PB1 Enhances the Immune Responses of Bone Marrow-Derived Dendritic Cells by Down-Regulating miR375." in: Frontiers in microbiology, Vol. 8, pp. 287, (2017) (PubMed).
: "The immunosuppressive characteristics of FB1 by inhibition of maturation and function of BMDCs." in: International immunopharmacology, Vol. 47, pp. 206-211, (2017) (PubMed).
Synonyme und alternative Namen zu IL12A
interleukin 12A (IL12A), interleukin 12B (IL12B), interleukin 12b (Il12b), interleukin 12B (Il12b), interleukin 12a (Il12a), interleukin 12A (Il12a), Interleukin 12 level (IL12), interleukin 12a (il12a), CLMF, CLMF2, Il-12 p35, IL-12 p35, IL-12A, Il-12a, IL-12B, Il-12b, IL-12p35, Il-12p40, IL-12p40, Il12, IL12, IL12p35, Il12p40, IL12p40, Ll12a, NFSK, NKSF, NKSF1, NKSF2, P35, p35, p40Bezeichner auf Proteinebene für IL12A
- CLMF p35
- IL-12 subunit p35
- IL-12, subunit p35
- IL35 subunit
- NF cell stimulatory factor chain 1
- NK cell stimulatory factor chain 1
- cytotoxic lymphocyte maturation factor 1, p35
- cytotoxic lymphocyte maturation factor 35 kDa subunit
- interleukin 12, p35
- interleukin-12 alpha chain
- interleukin-12 subunit alpha
- natural killer cell stimulatory factor 1, 35 kD subunit
- CLMF p40
- IL-12 subunit p40
- IL12, subunit p40
- NK cell stimulatory factor chain 2
- cytotoxic lymphocyte maturation factor 40 kDa subunit
- interleukin 12, p40
- interleukin-12 beta chain
- interleukin-12 subunit beta
- natural killer cell stimulatory factor, 40 kD subunit
- IL-12p35 subunit
- IL-12A
- interleukin 12
- IL-12 p40
- IL-23 subunit p40
- interleukin-12 p40
- IL-12B
- interleukin-12 p40 subunit
- interleukin 12B
- interleukin-12 p35 subunit
- IL-12 p40 subunit
- interleukin-12p40
- interleukin 12a p35 subunit
- interleukin 12 p35 subunit
- interleukin 12 35kDa subunit
- interleukin 12 polypeptide 35
- natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35
- IL-12 p35
- interleukin 12 40kDa subunit
- Cytotoxic lymphocyte maturation factor 35 kDa subunit
- interleukin 12 35kD subunit
- interleukin 12a
- interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
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