CSF1R Protein (His tag)

Produktnummer ABIN6961125

Produktdetails

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CSF1R Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant human CSF1R protein with C-terminal 6xHis tag

Spezifität: CSF1R (Ile20-Leu514) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CSF1R (CSF1R Produkte)

Synonyme: AI323359 Protein, CD115 Protein, CSF-1R Protein, Csfmr Protein, Fim-2 Protein, Fms Protein, M-CSF-R Protein, M-CSFR Protein, C-FMS Protein, CSFR Protein, FIM2 Protein, FMS Protein, HDLS Protein, PDGFRB Protein, MGC89146 Protein, CSF-1-R Protein, c-fms Protein, mrfms Protein, CSF1 Protein, M-CSF Protein, csf1r Protein, fms Protein, panther Protein, colony stimulating factor 1 receptor Protein, macrophage colony-stimulating factor receptor Protein, colony stimulating factor 1 receptor, a Protein, Csf1r Protein, CSF1R Protein, m-csfr Protein, csf1r Protein, csf1ra Protein

Hintergrund: Synonymes: CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR
Description: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

Molekulargewicht: predicted molecular mass of 55.6 kDa after removal of the signal peptide.

Gen-ID: 1436

UniProt: P07333

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization