LAMP1 Protein (AA 29-382) (His tag)

Produktnummer ABIN5855031

Produktdetails

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 29-382

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses LAMP1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPAMFMVKN GNGTACIMAN FSAAFSVNYD TKSGPKNMTF DLPSDATVVL NRSSCGKENT SDPSLVIAFG RGHTLTLNFT RNATRYSVQL MSFVYNLSDT HLFPNASSKE IKTVESITDI RADIDKKYRC VSGTQVHMNN VTVTLHDATI QAYLSNSSFS RGETRCEQDR PSPTTAPPAP PSPSPSPVPK SPSVDKYNVS GTNGTCLLAS MGLQLNLTYE RKDNTTVTRL LNINPNKTSA SGSCGAHLVT LELHSEGTTV LLFQFGMNAS SSRFFLQGIQ LNTILPDARD PAFKAANGSL RALQATVGNS YKCNAEEHVR VTKAFSVNIF KVWVQAFKVE GGQFGSVEEC LLDENSMHHH HHH

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Andere Bezeichnung: LAMP1 (LAMP1 Produkte)

Synonyme: CD107a Protein, LAMPA Protein, LGP120 Protein, AI196048 Protein, Lamp-1 Protein, LEP100 Protein, LAMP-1 Protein, LGP-A Protein, Lgpa Protein, Lysosome-associated membrane protein 1 Protein, cd107a Protein, lamp-1 Protein, lamp1 Protein, lampa Protein, lgp120 Protein, rexp76 Protein, lysosomal associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 L homeolog Protein, LAMP1 Protein, Lamp1 Protein, lamp1.L Protein

Hintergrund: LAMP1, also known as lysosome-associated membrane glycoprotein 1, is a membrane protein that belongs to the LAMP family. It is expressed in the endosome-lysosome membranes of cells, but is also found on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP1 is expressed on the surface of activated macrophages where it promotes T cell co-stimulation and a Th1 biased immune response. Recombinant human LAMP1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 39.4kDa (363aa) 57-70KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_005552

UniProt: P11279

Pathways: Autophagie