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LAMP1 Protein (Lysosomal-Associated Membrane Protein 1) (AA 29-382) (Fc Tag)

LAMP1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1691542
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  • Target Alle LAMP1 Proteine anzeigen
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 29-382
    Spezies
    • 7
    • 4
    • 1
    Human
    Quelle
    • 4
    • 3
    • 2
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses LAMP1 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human LAMP1/CD107a (C-Fc)
    Sequenz
    AMFMVKNGNG TACIMANFSA AFSVNYDTKS GPKNMTFDLP SDATVVLNRS SCGKENTSDP SLVIAFGRGH TLTLNFTRNA TRYSVQLMSF VYNLSDTHLF PNASSKEIKT VESITDIRAD IDKKYRCVSG TQVHMNNVTV TLHDATIQAY LSNSSFSRGE TRCEQDRPSP TTAPPAPPSP SPSPVPKSPS VDKYNVSGTN GTCLLASMGL QLNLTYERKD NTTVTRLLNI NPNKTSASGS CGAHLVTLEL HSEGTTVLLF QFGMNASSSR FFLQGIQLNT ILPDARDPAF KAANGSLRAL QATVGNSYKC NAEEHVRVTK AFSVNIFKVW VQAFKVEGGQ FGSVEECLLD ENSMVDDIEG RMDEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSREEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGK
    Produktmerkmale

    Recombinant Human LAMP1/CD107a (C-Fc)

    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Andere Bezeichnung
    Lysosome-Associated Membrane Glycoprotein 1/LAMP1 (LAMP1 Produkte)
    Synonyme
    CD107a, LAMPA, LGP120, AI196048, Lamp-1, LEP100, LAMP-1, LGP-A, Lgpa, Lysosome-associated membrane protein 1, cd107a, lamp-1, lamp1, lampa, lgp120, rexp76, lysosomal associated membrane protein 1, lysosomal-associated membrane protein 1, lysosomal-associated membrane protein 1 L homeolog, LAMP1, Lamp1, lamp1.L
    Hintergrund
    Recombinant Human Lysosome-Associated Membrane Glycoprotein 1/LAMP1 is produced by our mammalian expression system. The target protein is expressed with sequence (Ala29-Met382) of Human LAMP1fused with a FC tag at the C-terminus.
    Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
    Molekulargewicht
    65.5 kDa
    UniProt
    P11279
    Pathways
    Autophagie
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