LAMP1 Protein (Fc Tag)

Produktnummer ABIN7318714

Produktdetails

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses LAMP1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human LAMP1/CD107a Protein (Fc Tag)(Active)

Sequenz: Ala29-Met382

Produktmerkmale: Recombinant Human Lysosome-Associated Membrane Glycoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ala29-Met382 is expressed with a Fc tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human LGALS3(Cat: PKSH032474) at 2μg/ml(100 μl/well) can bind Human LAMP1-Fc. The ED50 of Human LAMP1-Fc is 1.994 ug/ml .

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Andere Bezeichnung: LAMP1/CD107a (LAMP1 Produkte)

Synonyme: CD107a Protein, LAMPA Protein, LGP120 Protein, AI196048 Protein, Lamp-1 Protein, LEP100 Protein, LAMP-1 Protein, LGP-A Protein, Lgpa Protein, Lysosome-associated membrane protein 1 Protein, cd107a Protein, lamp-1 Protein, lamp1 Protein, lampa Protein, lgp120 Protein, rexp76 Protein, lysosomal associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 L homeolog Protein, LAMP1 Protein, Lamp1 Protein, lamp1.L Protein

Hintergrund:

Background: Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.

Synonym: Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, Lysosome-Associated Membrane Protein 1, CD107 Antigen-Like Family Member A, CD107a, LAMP1,CD107a,LAMPA,LGP120

Molekulargewicht: 65.5 kDa

UniProt: P11279

Pathways: Autophagie