LAMP1 Protein (His tag)

Produktnummer ABIN7534641

Produktdetails

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LAMP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Active Recombinant Human LAMP-1/CD107a Protein

Sequenz: AMFMVKNGNG TACIMANFSA AFSVNYDTKS GPKNMTFDLP SDATVVLNRS SCGKENTSDP SLVIAFGRGH TLTLNFTRNA TRYSVQLMSF VYNLSDTHLF PNASSKEIKT VESITDIRAD IDKKYRCVSG TQVHMNNVTV TLHDATIQAY LSNSSFSRGE TRCEQDRPSP TTAPPAPPSP SPSPVPKSPS VDKYNVSGTN GTCLLASMGL QLNLTYERKD NTTVTRLLNI NPNKTSASGS CGAHLVTLEL HSEGTTVLLF QFGMNASSSR FFLQGIQLNT ILPDARDPAF KAANGSLRAL QATVGNSYKC NAEEHVRVTK AFSVNIFKVW VQAFKVEGGQ FGSVEECLLD ENSM

Spezifität: Ala29-Met382

Reinheit: > 97 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human LAMP1 at 1 μg/mL (100 μL/well) can bind LAMP1 Rabbit pAb with a linear range of 1-8.5 ng/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Antigendetails

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Andere Bezeichnung: LAMP-1/CD107a (LAMP1 Produkte)

Synonyme: CD107a Protein, LAMPA Protein, LGP120 Protein, AI196048 Protein, Lamp-1 Protein, LEP100 Protein, LAMP-1 Protein, LGP-A Protein, Lgpa Protein, Lysosome-associated membrane protein 1 Protein, cd107a Protein, lamp-1 Protein, lamp1 Protein, lampa Protein, lgp120 Protein, rexp76 Protein, lysosomal associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 L homeolog Protein, LAMP1 Protein, Lamp1 Protein, lamp1.L Protein

Hintergrund:

Description: Lysosomal associated membrane protein 1 (LAMP1), also known as CD107a, is a single-pass type I membrane protein which belongs to the LAMP family.LAMP-1 is a glycoprotein highly expressed in lysosomal membranes.This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. LAMP-1 acts as a receptor for Lassa virus protein. LAMP1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets.

Name: LAMP1, CD107a, LAMPA, LGP120, lysosomal associated membrane protein 1,CD107a,LAMPA,LGP120

Gen-ID: 3916

UniProt: P11279-1

Pathways: Autophagie