PKC beta Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729604

Produktdetails

Target: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PKC beta Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PRKCB (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Andere Bezeichnung: Prkcb (PRKCB Produkte)

Synonyme: PKC-beta Protein, PKCB Protein, PRKCB1 Protein, PRKCB2 Protein, A130082F03Rik Protein, PKC-Beta Protein, Pkcb Protein, Prkcb1 Protein, Prkcb2 Protein, PKC-B Protein, Prkcb Protein, prkcb1 Protein, zgc:63591 Protein, PKC Protein, PRKCB_tv2 Protein, Pkc53E Protein, prkcb1l Protein, zgc:64063 Protein, protein kinase C beta Protein, protein kinase C, beta Protein, protein kinase C, beta b Protein, protein kinase C, beta a Protein, PRKCB Protein, Prkcb Protein, prkcbb Protein, prkcba Protein

Hintergrund: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 76.7 kDa

NCBI Accession: NP_997700

Pathways: WNT Signalweg, T-Zell Rezeptor Signalweg, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling