anti-Rind (Kuh) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antikörper für Immunohistochemistry

Recommended Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibody

Antigen
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antikörper
  • GR
  • gcr
  • grl
  • xGR
  • gccr
  • gr
  • zgc:113038
  • NR3C1
  • GCL
  • LOC100302444
  • Gcr
  • Grl
  • Grl-1
  • Grl1
  • GRL
  • GCCR
  • GCR
  • NO
  • GR-A
  • nr3c1
  • nuclear receptor subfamily 3 group C member 1
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
  • nuclear receptor subfamily 3, group C, member 1
  • glucocorticoid receptor
  • NR3C1
  • nr3c1
  • LOC100302444
  • Nr3c1
Epitop
N-Term
26
25
21
18
18
16
13
11
10
10
7
7
7
6
5
5
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Meerschweinchen, Pferd, Human, Maus, Schwein, Ratte (Rattus)
298
155
138
7
7
5
5
5
4
3
2
1
1
1
Wirt
Kaninchen
257
59
5
Klonalität
Polyklonal
Konjugat
Unkonjugiert
23
20
10
7
6
6
6
6
6
6
6
6
3
3
3
3
3
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
235
123
107
64
56
39
36
29
27
18
4
3
2
1
1
Optionen

Bilder

Produktnummer ABIN2782262
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
10.05975 ABIN2706239 IHC WB Rabbit pSer211 Polyclonal 0
10.05975 ABIN2777208 IHC WB Rabbit N-Term Polyclonal 0
10.05975 ABIN2971701 IHC WB Rabbit Center, pSer211 Polyclonal 0
9.389946 ABIN152763 ChIP ICC IF IHC (p) IHC WB Rabbit IgG Polyclonal 1
7.05975 ABIN6748602 IHC IHC (p) WB Rabbit AA 180-229 Polyclonal 0
1 ABIN2743324 IHC IHC (p) WB Rabbit pSer211 Polyclonal 0
1 ABIN1918434 IF IHC IHC (p) IP WB Rabbit IgG AA 150-200 Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antikörper
Epitop N-Term
(26), (25), (21), (18), (18), (16), (13), (11), (10), (10), (7), (7), (7), (6), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Meerschweinchen, Pferd, Human, Maus, Schwein, Ratte (Rattus)
(298), (155), (138), (7), (7), (5), (5), (5), (4), (3), (2), (1), (1), (1)
Wirt Kaninchen
(257), (59), (5)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(23), (20), (10), (7), (6), (6), (6), (6), (6), (6), (6), (6), (3), (3), (3), (3), (3), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(235), (123), (107), (64), (56), (39), (36), (29), (27), (18), (4), (3), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN980920.
Sequenz NVKLYTTDQS TFDILQDLEF SSGSPGKETN ESPWRSDLLI DENCLLSPLA
Homologie Cow: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against NR3C1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung NR3C1 (NR3C1 Antibody Abstract)
Hintergrund NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
Alias Symbols: GCCR, GCR, GR, GRL
Protein Interaction Partner: TTC5, HSP90AA1, TXN2, UBC, TXN, FKBP5, DCAF6, RABEP2, BRCC3, LARP7, GAPVD1, CD2AP, SF3A1, HNRNPR, TRIM28, HDAC1, MTA2, CCDC6, CENPB, TMF1, PPARG, STUB1, BAG1, RPS6KA5, NCOA1, POLR1D, NCOA2, SRA1, PRKDC, RAD54L2, MAGEA11, PPP5C, PPID, GNB2, GNB1, FKBP4, GN
Protein Size: 777
Molekulargewicht 86 kDa
Gen-ID 2908
NCBI Accession NM_000176, NP_000167
UniProt P04150
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 777 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Yoshikawa, Shimizu, Sano, Ohnuma, Iwata, Hosono, Fukuda, Morimoto, Tanaka: "Role of the hinge region of glucocorticoid receptor for HEXIM1-mediated transcriptional repression." in: Biochemical and biophysical research communications, Vol. 371, Issue 1, pp. 44-9, 2008

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (N-Term) antibody (ABIN2782262) WB Suggested Anti-NR3C1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posi...
Immunohistochemistry (IHC) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (N-Term) antibody (ABIN2782262) Immunohistochemistry with Colon, submucosal plexus tissue at an antibody concentratio...
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (N-Term) antibody (ABIN2782262) Host: Rabbit Target Name: NR3C1 Sample Type: Hela Antibody Dilution: 1.0ug/ml