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Glucocorticoid Receptor Produkte

(Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

Kategorien

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011].

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Ausgewählte Glucocorticoid Receptor Kategorien

Glucocorticoid Receptor Antikörper

High quality antibodies with extensive validation data.

Glucocorticoid Receptor ELISA Kits

Reliable ELISA kits for a wide range of species.

Glucocorticoid Receptor Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Glucocorticoid Receptor Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (3)
  • (6)
Kat. Nr. ABIN3023091
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, ICC, FACS
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN969321
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), IP, ICC
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN2854939
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Glucocorticoid Receptor ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (5)
Kat. Nr. ABIN6720464
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958262
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969020
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Glucocorticoid Receptor Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312973
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312972
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3092736
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Glucocorticoid Receptor Produkten

Miranda, Pietrobon, Bertasso, Rodrigues, Lopes, Calvino, de Oliveira, de Moura, Lisboa: "Early weaning leads to specific glucocorticoid signalling in fat depots of adult rats." in: Endocrine, Vol. 67, Issue 1, pp. 180-189, (2020) (PubMed).

Okada, Okada: "Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells." in: Molecular biology reports, Vol. 47, Issue 2, pp. 1021-1032, (2020) (PubMed).

Taves, Mittelstadt, Presman, Hager, Ashwell: "Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus." in: Cell reports, Vol. 26, Issue 13, pp. 3629-3642.e4, (2019) (PubMed).

Adams, Smith: "Chronic Gestational Inflammation: Transfer of Maternal Adaptation over Two Generations of Progeny." in: Mediators of inflammation, Vol. 2019, pp. 9160941, (2019) (PubMed).

Liu, Chen, Pei, Zhang, Zou, Xiao, Zhou, Chen, Wang: "Decreased H3K9ac level of StAR mediated testicular dysplasia induced by prenatal dexamethasone exposure in male offspring rats." in: Toxicology, Vol. 408, pp. 1-10, (2018) (PubMed).

Guo, Ma, Xia, Chen, Li, Deng, Sheng, Hong, Hu: "Androgen receptor reverts dexamethasone‑induced inhibition of prostate cancer cell proliferation and migration." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5887-5893, (2018) (PubMed).

Roh, Park, Jung: "Inhibitory Effects of Prunella vulgaris L. Extract on 11β-HSD1 in Human Skin Cells." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 1762478, (2018) (PubMed).

Yi, Shi, Wang, Ma, Zhang, Wang, Cong, Li: "Endoplasmic Reticulum Stress PERK-ATF4-CHOP Pathway Is Associated with Hypothalamic Neuronal Injury in Different Durations of Stress in Rats." in: Frontiers in neuroscience, Vol. 11, pp. 152, (2017) (PubMed).

Sharma, Maras, Das, Hussain, Mishra, Shasthry, Sharma, Weiss, Elkrief, Rautou, Gilgenkrantz, Lotersztajn, Paradis, de la Grange, Junot, Moreau, Sarin: "Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness." in: Scientific reports, Vol. 7, Issue 1, pp. 6816, (2017) (PubMed).

Rué, Bañez-Coronel, Creus-Muncunill, Giralt, Alcalá-Vida, Mentxaka, Kagerbauer, Zomeño-Abellán, Aranda, Venturi, Pérez-Navarro, Estivill, Martí: "Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels." in: The Journal of clinical investigation, Vol. 126, Issue 11, pp. 4319-4330, (2016) (PubMed).

Synonyme und alternative Namen zu Glucocorticoid Receptor

nuclear receptor subfamily 3 group C member 1 (NR3C1), nuclear receptor subfamily 3 group C member 1 (nr3c1), nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (nr3c1), nuclear receptor subfamily 3, group C, member 1 (NR3C1), glucocorticoid receptor (LOC100302444), nuclear receptor subfamily 3, group C, member 1 (Nr3c1), nuclear receptor subfamily 3 group C member 1 (Nr3c1), nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), gccr, GCCR, GCL, gcr, Gcr, GCR, GR, gr, GR-A, grl, Grl, GRL, Grl-1, Grl1, LOC100302444, NO, NR3C1, nr3c1, xGR, zgc:113038

Bezeichner auf Proteinebene für Glucocorticoid Receptor

  • glucocorticoid receptor
  • nuclear receptor subfamily 3, group C, member 1
  • glucocorticoid receptor 1
  • GR
  • nuclear receptor subfamily 3 group C member 1
  • glucocorticoid nuclear receptor variant 1
  • glucocorticoid receptor alpha
  • glucocorticoid receptor variant P
  • glucocorticoid receptor variant beta
  • glucocorticoid receptor variant gamma
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