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Human Polyclonal MECP2 Primary Antibody für ICC, IF - ABIN269308
LaSalle, Goldstine, Balmer, Greco: Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry. in Human molecular genetics 2001
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Human Monoclonal MECP2 Primary Antibody für ChIP, ICC - ABIN2668836
Ganguly, Chen, Shin, Devaskar: Prenatal caloric restriction enhances DNA methylation and MeCP2 recruitment with reduced murine placental glucose transporter isoform 3 expression. in The Journal of nutritional biochemistry 2014
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Human Polyclonal MECP2 Primary Antibody für ICC, IF - ABIN252309
Ruddock-DCruz, Xue, Wilson, Heffernan, Prashadkumar, Cooney, Sanchez-Partida, French, Holland: Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development. in Molecular reproduction and development 2007
Human Polyclonal MECP2 Primary Antibody für ICC, IF - ABIN4333391
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Human Monoclonal MECP2 Primary Antibody für ChIP, ICC - ABIN2668837
Jost, Rottach, Milden, Bertulat, Becker, Wolf, Sandoval, Petazzi, Huertas, Esteller, Kremmer, Leonhardt, Cardoso: Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies. in PLoS ONE 2011
Cow (Bovine) Polyclonal MECP2 Primary Antibody für WB - ABIN2781332
Robertson, Hall, Jacoby, Ellaway, de Klerk, Leonard: The association between behavior and genotype in Rett syndrome using the Australian Rett Syndrome Database. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006
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DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
, methyl-CpG-binding protein 2
, meCP-2 protein
, methyl-CpG-binding protein MeCP2