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MECP2 Antikörper (AA 7-148)

MECP2 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 8H4A5B9 unconjugated
Produktnummer ABIN5542475
  • Target Alle MECP2 Antikörper anzeigen
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Bindungsspezifität
    • 19
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 7-148
    Reaktivität
    • 104
    • 41
    • 31
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 104
    • 7
    • 1
    Maus
    Klonalität
    • 105
    • 7
    Monoklonal
    Konjugat
    • 66
    • 10
    • 8
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MECP2 Antikörper ist unkonjugiert
    Applikation
    • 82
    • 65
    • 35
    • 30
    • 13
    • 10
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human MECP2 (AA: 7-148) expressed in E. coli.
    Klon
    8H4A5B9
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Andere Bezeichnung
    MECP2 (MECP2 Produkte)
    Synonyme
    AUTSX3 antikoerper, MRX16 antikoerper, MRX79 antikoerper, MRXS13 antikoerper, MRXSL antikoerper, PPMX antikoerper, RS antikoerper, RTS antikoerper, RTT antikoerper, 1500041B07Rik antikoerper, BB130002 antikoerper, D630021H01Rik antikoerper, Mbd5 antikoerper, WBP10 antikoerper, wu:fk96a04 antikoerper, zgc:111857 antikoerper, methyl-CpG binding protein 2 antikoerper, methyl CpG binding protein 2 antikoerper, methyl-CpG binding protein 2 S homeolog antikoerper, MECP2 antikoerper, Mecp2 antikoerper, mecp2 antikoerper, mecp2.S antikoerper
    Hintergrund

    Description: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.,

    Aliases: RS, RTS, RTT, PPMX, MRX16, MRX79, MRXSL, AUTSX3, MRXS13

    Molekulargewicht
    52.4 kDa
    Gen-ID
    4204
    HGNC
    4204
    Pathways
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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