MECP2 Produkte
(Methyl CpG Binding Protein 2 (MECP2))
Kategorien
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009].
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Ausgewählte MECP2 Kategorien
MECP2 Antikörper
High quality antibodies with extensive validation data.
MECP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
MECP2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MECP2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (8)
Kat. Nr.
ABIN5542475
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, IHC (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN650833
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN517816
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene MECP2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962645
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968595
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960688
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MECP2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1310622
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123936
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310624
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MECP2 Produkten
: "Linc-ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR-194-3p targeting MECP2." in: Molecular oncology, Vol. 14, Issue 9, pp. 2231-2250, (2021) (PubMed).: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." in: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).
: "An electrochemiluminescence based assay for quantitative detection of endogenous and exogenously applied MeCP2 protein variants." in: Scientific reports, Vol. 9, Issue 1, pp. 7929, (2020) (PubMed).
: "The significance of the increased expression of phosphorylated MeCP2 in the membranes from patients with proliferative diabetic retinopathy." in: Scientific reports, Vol. 6, pp. 32850, (2018) (PubMed).
: "Expression of Phospho-MeCP2s in the Developing Rat Brain and Function of Postnatal MeCP2 in Cerebellar Neural Cell Development." in: Neuroscience bulletin, Vol. 33, Issue 1, pp. 1-16, (2017) (PubMed).
: "CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression." in: Nature communications, Vol. 8, Issue 1, pp. 355, (2017) (PubMed).
: "Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology." in: Frontiers in molecular neuroscience, Vol. 10, pp. 69, (2017) (PubMed).
: "Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior." in: Nature neuroscience, Vol. 19, Issue 11, pp. 1497-1505, (2016) (PubMed).
: "MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome." in: Nature communications, Vol. 7, pp. 10552, (2016) (PubMed).
: "Geniposide alleviates inflammation by suppressing MeCP2 in mice with carbon tetrachloride-induced acute liver injury and LPS-treated THP-1 cells." in: International immunopharmacology, (2015) (PubMed).
Synonyme und alternative Namen zu MECP2
methyl-CpG binding protein 2 (MECP2), methyl CpG binding protein 2 (Mecp2), methyl CpG binding protein 2 (mecp2), methyl-CpG binding protein 2 S homeolog (mecp2.S), 1500041B07Rik, AUTSX3, BB130002, D630021H01Rik, Mbd5, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, WBP10, wu:fk96a04, zgc:111857Bezeichner auf Proteinebene für MECP2
- meCp-2 protein
- methyl-CpG-binding protein 2
- meCP-2 protein
- methyl-CpG-binding protein MeCP2
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