MED23 Produkte
(Mediator Complex Subunit 23 (MED23))
Kategorien
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012].
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Ausgewählte MED23 Kategorien
MED23 Antikörper
High quality antibodies with extensive validation data.
MED23 ELISA Kits
Reliable ELISA kits for a wide range of species.
MED23 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MED23 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7159128
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, IHC
Validierungen
- (1)
Kat. Nr.
ABIN7003463
Menge
20 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC, IF
Validierungen
- (1)
Kat. Nr.
ABIN7188664
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene MED23 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1743282
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1774187
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1744501
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MED23 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310655
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3093769
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3136081
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MED23 Produkten
: "Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development." in: Nature communications, Vol. 7, pp. 11149, (2016) (PubMed).: "LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation." in: Neuron, Vol. 86, Issue 3, pp. 696-710, (2015) (PubMed).
: "The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination." in: The EMBO journal, Vol. 34, Issue 23, pp. 2885-902, (2015) (PubMed).
: "T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs." in: PLoS ONE, Vol. 9, Issue 7, pp. e102076, (2015) (PubMed).
: "The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation." in: Experimental neurology, Vol. 253, pp. 126-37, (2014) (PubMed).
: "Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity." in: Cell research, Vol. 24, Issue 10, pp. 1250-65, (2014) (PubMed).
: "Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation." in: Journal of virology, Vol. 86, Issue 15, pp. 8198-209, (2012) (PubMed).
: "Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves." in: Molecular and cellular biology, Vol. 32, Issue 1, pp. 199-205, (2011) (PubMed).
: "Core promoter recognition complex changes accompany liver development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 10, pp. 3906-11, (2011) (PubMed).
: "Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3." in: The EMBO journal, Vol. 27, Issue 10, pp. 1447-57, (2008) (PubMed).
Synonyme und alternative Namen zu MED23
Mediator complex subunit 23 (MED23), mediator complex subunit 23 (MED23), mediator complex subunit 23 (med23), mediator of RNA polymerase II transcription subunit 23 (LOC412332), mediator complex subunit 23 (Med23), mediator complex subunit 23 L homeolog (med23.L), Mediator of RNA polymerase II transcription subunit 23 (sur-2), 130kDa, 3000002A17Rik, ARC130, CG3695, CRSP3, Crsp3, crsp3, CRSP130, CRSP133, Dmel\\CG3695, DRIP130, dSUR2, dTRAP150beta, ESTM7, Gal11/SUR2, Med23, MED23, mKIAA1216, MRT18, si:ch211-272f15.2, SUR-2, SUR2, Sur2, Trap150, Trap150beta, X83317, zgc:91979Bezeichner auf Proteinebene für MED23
- CG3695-PA
- CG3695-PB
- MED23-PA
- MED23-PB
- mediator complex subunit 23
- mediator complex subunit n23
- cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa
- Sp1 transcriptional activation cofactor subunit 3
- mediator of RNA polymerase II transcription subunit 23-like
- mediator of RNA polymerase II transcription subunit 23
- 130 kDa transcriptional co-activator
- 133 kDa transcriptional co-activator
- activator-recruited cofactor 130 kDa component
- cofactor required for Sp1 transcriptional activation subunit 3
- vitamin D3 receptor interacting protein
- CRSP complex subunit 3
- cofactor required for Sp1 transcriptional activation, subunit 3 (130kD)
- mSur-2
- protein sur-2 homolog
- cofactor required for Sp1 transcriptional activation, subunit 3
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