HLA-DR-gamma Produkte
(HLA-DR-gamma (CD74))
Kategorien
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Ausgewählte HLA-DR-gamma Kategorien
HLA-DR-gamma Antikörper
High quality antibodies with extensive validation data.
HLA-DR-gamma ELISA Kits
Reliable ELISA kits for a wide range of species.
HLA-DR-gamma Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HLA-DR-gamma Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, ELISA, ICC
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN1724871
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IF, IHC
Validierungen
- (9)
Kat. Nr.
ABIN7074245
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7443692
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene HLA-DR-gamma ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962624
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967449
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956587
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HLA-DR-gamma Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274222
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274239
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1348699
Menge
25 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HLA-DR-gamma Produkten
: "Association of variant on the promoter of cluster of differentiation 74 in graves disease and graves ophthalmopathy." in: Bioscience reports, Vol. 40, Issue 8, (2020) (PubMed).: "Examining epitope mutagenesis as a strategy to reduce and eliminate human antibody binding to class II swine leukocyte antigens." in: Immunogenetics, Vol. 71, Issue 7, pp. 479-487, (2019) (PubMed).
: "Synergy between B cell receptor/antigen uptake and MHCII peptide editing relies on HLA-DO tuning." in: Scientific reports, Vol. 9, Issue 1, pp. 13877, (2019) (PubMed).
: "Examining the Biosynthesis and Xenoantigenicity of Class II Swine Leukocyte Antigen Proteins." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 8, pp. 2957-2964, (2018) (PubMed).
: "Expression of macrophage migration inhibitory factor and CD74 in the inner ear and middle ear in lipopolysaccharide-induced otitis media." in: Acta oto-laryngologica, Vol. 136, Issue 10, pp. 1011-6, (2016) (PubMed).
: "Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-γ." in: The Journal of investigative dermatology, Vol. 135, Issue 11, pp. 2775-84, (2015) (PubMed).
: "A conserved WW domain-like motif regulates invariant chain-dependent cell-surface transport of the NKG2D ligand ULBP2." in: Molecular immunology, Vol. 66, Issue 2, pp. 418-27, (2015) (PubMed).
: "Autoantibodies against CD74 in spondyloarthritis." in: Annals of the rheumatic diseases, Vol. 73, Issue 6, pp. 1211-4, (2014) (PubMed).
: "Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells." in: Biochemical and biophysical research communications, Vol. 451, Issue 1, pp. 48-53, (2014) (PubMed).
: "CD74: a new prognostic factor for patients with malignant pleural mesothelioma." in: British journal of cancer, Vol. 110, Issue 8, pp. 2040-6, (2014) (PubMed).
Synonyme und alternative Namen zu HLA-DR-gamma
CD74 molecule (CD74), CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74), CD74 molecule (Cd74), CD74 molecule, major histocompatibility complex, class II invariant chain a (cd74a), CD74 molecule, major histocompatibility complex, class II invariant chain b (cd74b), cd74, CLIP, DHLAG, HLADG, Ia-GAMMA, Iclp-1, Iclp-2, iclp1, iclp2, II, Ii, INVG34, wu:fb11f09, wu:fb12a01, wu:fb13d06, wu:fk94e07, zgc:123161Bezeichner auf Proteinebene für HLA-DR-gamma
- CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
- HLA class II histocompatibility antigen gamma chain
- HLA-DR antigens-associated invariant chain
- HLA-DR-gamma
- Ia-associated invariant chain
- MHC HLA-DR gamma chain
- gamma chain of class II antigens
- p33
- H-2 class II histocompatibility antigen gamma chain
- HLA-DR-GAMMA
- MHC class II-associated invariant chain
- class II-associated invariant chain peptide
- dinucleotide microsatellite
- histocompatibility: class II antigens, gamma chain of
- ia antigen-associated invariant chain
- invariant polypeptide of major histocompatibility complex, class II antigen-associated
- ii
- CD74 molecule, major histocompatibility complex, class II invariant chain
- CD74 molecule, major histocompatibility complex, class II invariant chain a
- MHC II
- invariant chain-like protein 1
- invariant chain-like protein 2
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