HLA-DQB1 Produkte
(Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1))
Kategorien
HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].
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Ausgewählte HLA-DQB1 Kategorien
HLA-DQB1 Antikörper
High quality antibodies with extensive validation data.
HLA-DQB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
HLA-DQB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HLA-DQB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7155597
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (4)
Kat. Nr.
ABIN1327606
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (4)
- (1)
Kat. Nr.
ABIN1881422
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene HLA-DQB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957623
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957624
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HLA-DQB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306759
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306761
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3092196
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HLA-DQB1 Produkten
: "Follicular lymphoma-protective HLA class II variants correlate with increased HLA-DQB1 protein expression." in: Genes and immunity, Vol. 15, Issue 2, pp. 133-6, (2014) (PubMed).: "Exon-intron organization and complete nucleotide sequence of a human major histocompatibility antigen DC beta gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 80, Issue 23, pp. 7313-7, (1984) (PubMed).
: "Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, Issue 16, pp. 5199-203, (1984) (PubMed).
: "Molecular analysis of human class II transplantation antigens and their genes." in: Human immunology, Vol. 8, Issue 1, pp. 95-103, (1983) (PubMed).
: "Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, Issue 12, pp. 3687-91, (1982) (PubMed).
Synonyme und alternative Namen zu HLA-DQB1
major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), major histocompatibility complex, class II, DQ beta 1 (PATR-DQB1), major histocompatibility complex, class II, DQ beta 1 (DLA-DQB1), major histocompatibility complex, class II, DQ beta 1 (MAMU-DQB1), major histocompatibility complex, class II, DQ beta 1 (LOC100172120), CELIAC1, DKFZp469C0237, DLA-DQB, HLA-DQB, IDDM1, LOC100172120, MAMU-DQB1, mhc-DRBBezeichner auf Proteinebene für HLA-DQB1
- HLA class II histocompatibility antigen, DQ beta 1 chain
- MHC DQ beta
- MHC class II DQ beta chain
- MHC class II HLA-DQ beta glycoprotein
- MHC class II antigen DQB1
- MHC class II antigen HLA-DQ-beta-1
- MHC class2 antigen
- lymphocyte antigen
- MHC class II DRB antigen
- MHC class II DLA DQ beta chain
- major histocompatibility complex, class II, DQ beta 1
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