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HLAG Produkte

(HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008].

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Ausgewählte HLAG Kategorien

HLAG Antikörper

High quality antibodies with extensive validation data.

HLAG ELISA Kits

Reliable ELISA kits for a wide range of species.

HLAG Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HLAG Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (fro), IHC (p)
Validierungen
  • (10)
  • (5)
Kat. Nr. ABIN94366
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS
Validierungen
  • (11)
  • (5)
Kat. Nr. ABIN94373
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, FACS, IHC (fro), IP, ICC
Validierungen
  • (15)
  • (4)
Kat. Nr. ABIN94369
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene HLAG ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN6956586
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962367
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN809034
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HLAG Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7274817
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274813
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274818
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HLAG Produkten

Horii, Bui, Touma, Cho, Parast: "An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells." in: Current protocols in stem cell biology, Vol. 50, Issue 1, pp. e96, (2020) (PubMed).

Jørgensen, Sayed, Jeppesen, Persson, Weisdorf, Funck, Hviid: "Characterization of HLA-G Regulation and HLA Expression in Breast Cancer and Malignant Melanoma Cell Lines upon IFN-γ Stimulation and Inhibition of DNA Methylation." in: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).

Vossaert, Wang, Salman, McCombs, Patel, Qu, Mancini, Edwards, Malovannaya, Liu, Shaw, Levy, Wapner, Bi, Breman, Van den Veyver, Beaudet: "Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis." in: American journal of human genetics, Vol. 105, Issue 6, pp. 1262-1273, (2019) (PubMed).

Eche, Mackraj, Moodley: "Circulating fetal and total cell-free DNA, and sHLA-G in black South African women with gestational hypertension and pre-eclampsia." in: Hypertension in pregnancy, Vol. 36, Issue 4, pp. 295-301, (2018) (PubMed).

Spurny, Kailayangiri, Altvater, Jamitzky, Hartmann, Wardelmann, Ranft, Dirksen, Amler, Hardes, Fluegge, Meltzer, Farwick, Greune, Rossig: "T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G." in: Oncotarget, Vol. 9, Issue 5, pp. 6536-6549, (2018) (PubMed).

Chen, Liang, Yao, Chen, Shi, Zhang, Zhao, Zhang, Sun: "Mesenchymal stem cells upregulate Treg cells via sHLA-G in SLE patients." in: International immunopharmacology, Vol. 44, pp. 234-241, (2017) (PubMed).

Haider, Meinhardt, Saleh, Fiala, Pollheimer, Knöfler: "Notch1 controls development of the extravillous trophoblast lineage in the human placenta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 48, pp. E7710-E7719, (2016) (PubMed).

Liu, Hu, Zheng, Liu, Luo, Liu, Zhao, Zou: "EPHB4 Regulates Human Trophoblast Cell Line HTR-8/SVneo Function: Implications for the Role of EPHB4 in Preeclampsia." in: Biology of reproduction, Vol. 95, Issue 3, pp. 65, (2016) (PubMed).

Guo, Lv, Wang, Shi, Yang, Zheng, Wen, Yang: "Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients." in: Cellular immunology, Vol. 293, Issue 1, pp. 10-6, (2015) (PubMed).

Favoino, Favia, Vettori, Vicenti, Prete, Valentini, Perosa: "Clinical correlates of human leucocyte antigen (HLA)-G in systemic sclerosis." in: Clinical and experimental immunology, Vol. 181, Issue 1, pp. 100-9, (2015) (PubMed).

Synonyme und alternative Namen zu HLAG

major histocompatibility complex, class I, G (HLA-G), MHC BF1 class I (BF1), B-F, B-F-S04, B-F-S05, B-F-S06, B-F-S07, B-FI, B-FIV, BF2, BFa2, BFw-03, BFw-05, BFz-01, MHC-G

Bezeichner auf Proteinebene für HLAG

  • HLA G antigen
  • HLA class I histocompatibility antigen, alpha chain G
  • HLA class I molecule
  • HLA-G histocompatibility antigen, class I, G
  • MHC class I antigen G
  • b2 microglobulin
  • B-F minor
  • MHC class I antigen alpha chain
  • MHC class I glycoprotein
  • major histocompatibility complex, class I, G
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