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CD74 Antikörper

CD74 Reaktivität: Maus, Ratte IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074245
  • Target Alle CD74 Antikörper anzeigen
    CD74 (HLA-DR-gamma (CD74))
    Reaktivität
    • 183
    • 64
    • 12
    • 11
    Maus, Ratte
    Wirt
    • 121
    • 79
    • 4
    • 2
    Kaninchen
    Klonalität
    • 138
    • 66
    • 2
    Polyklonal
    Konjugat
    • 70
    • 17
    • 16
    • 10
    • 10
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD74 Antikörper ist unkonjugiert
    Applikation
    • 125
    • 111
    • 77
    • 43
    • 36
    • 36
    • 30
    • 27
    • 18
    • 14
    • 13
    • 11
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse CD74
    Top Product
    Discover our top product CD74 Primärantikörper
  • Applikationshinweise
    IHC/IF (M,R) 1:1000-1:4000/1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    CD74 (HLA-DR-gamma (CD74))
    Andere Bezeichnung
    CD74 (CD74 Produkte)
    Synonyme
    DHLAG antikoerper, HLADG antikoerper, II antikoerper, Ia-GAMMA antikoerper, CLIP antikoerper, Ii antikoerper, INVG34 antikoerper, Iclp-1 antikoerper, iclp1 antikoerper, wu:fb11f09 antikoerper, wu:fb12a01 antikoerper, wu:fb13d06 antikoerper, wu:fk94e07 antikoerper, Iclp-2 antikoerper, cd74 antikoerper, iclp2 antikoerper, zgc:123161 antikoerper, CD74 molecule antikoerper, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antikoerper, CD74 molecule, major histocompatibility complex, class II invariant chain a antikoerper, CD74 molecule, major histocompatibility complex, class II invariant chain b antikoerper, CD74 antikoerper, Cd74 antikoerper, cd74a antikoerper, cd74b antikoerper
    Hintergrund
    CD74, also known as the MHC class II associated invariant chain (Ii), is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of or in association with MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized.
    Gen-ID
    16149
    NCBI Accession
    NP_001036070
    UniProt
    P04441
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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