TLE1 Antikörper (Middle Region)

Produktnummer ABIN955230

Produktdetails anti-TLE1 Antikörper

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Bindungsspezifität: AA 206-236, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects TLE1 (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 206~236 amino acids from the Central region of human TLE1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Andere Bezeichnung: TLE1 (TLE1 Produkte)

Synonyme: ESG antikoerper, ESG1 antikoerper, GRG1 antikoerper, C230057C06Rik antikoerper, Estm14 antikoerper, Grg1 antikoerper, Tle4l antikoerper, TLE1 antikoerper, transducin like enhancer of split 1 antikoerper, transducin-like enhancer protein 1 antikoerper, transducin-like enhancer of split 1 antikoerper, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antikoerper, TLE1 antikoerper, Smp_150080 antikoerper, Tle1 antikoerper, LOC100354911 antikoerper, LOC100524475 antikoerper, LOC100061341 antikoerper

Hintergrund: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.Synonyms: ESG1, Enhancer of split groucho-like protein 1, Transducin-like enhancer protein 1

Gen-ID: 7088

NCBI Accession: NP_005068

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom