TLE1 Antikörper (Internal Region)

Produktnummer ABIN6265592

Produktdetails anti-TLE1 Antikörper

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: TLE1 Antibody detects endogenous levels of total TLE1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TLE1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Andere Bezeichnung: TLE1 (TLE1 Produkte)

Synonyme: ESG antikoerper, ESG1 antikoerper, GRG1 antikoerper, C230057C06Rik antikoerper, Estm14 antikoerper, Grg1 antikoerper, Tle4l antikoerper, TLE1 antikoerper, transducin like enhancer of split 1 antikoerper, transducin-like enhancer protein 1 antikoerper, transducin-like enhancer of split 1 antikoerper, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antikoerper, TLE1 antikoerper, Smp_150080 antikoerper, Tle1 antikoerper, LOC100354911 antikoerper, LOC100524475 antikoerper, LOC100061341 antikoerper

Hintergrund:

Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Gene: TLE1

Molekulargewicht: 83kDa

Gen-ID: 7088

UniProt: Q04724

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom