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TLE1 Antikörper (AA 175-338)

TLE1 Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal TLE1-2051 unconjugated
Produktnummer ABIN6940747
  • Target Alle TLE1 Antikörper anzeigen
    TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
    Bindungsspezifität
    • 12
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-338
    Reaktivität
    • 59
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 16
    • 1
    Maus
    Klonalität
    • 42
    • 18
    Monoklonal
    Konjugat
    • 38
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLE1 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 25
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human TLE1 fragment (aa 175-338) (exact sequence is proprietary)
    Klon
    TLE1-2051
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product TLE1 Primärantikörper
  • Applikationshinweise

    Positive Control: HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas.

    Known Application: Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
    Andere Bezeichnung
    TLE1 (TLE1 Produkte)
    Synonyme
    ESG antikoerper, ESG1 antikoerper, GRG1 antikoerper, C230057C06Rik antikoerper, Estm14 antikoerper, Grg1 antikoerper, Tle4l antikoerper, TLE1 antikoerper, transducin like enhancer of split 1 antikoerper, transducin-like enhancer protein 1 antikoerper, transducin-like enhancer of split 1 antikoerper, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antikoerper, TLE1 antikoerper, Smp_150080 antikoerper, Tle1 antikoerper, LOC100354911 antikoerper, LOC100524475 antikoerper, LOC100061341 antikoerper
    Hintergrund
    Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein1 (TLE1) is a protein that isencoded by theTLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
    Molekulargewicht
    83kDa
    Gen-ID
    7088
    UniProt
    Q04724
    Pathways
    WNT Signalweg, SARS-CoV-2 Protein Interaktom
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